File:Nephron development 01.jpg
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Nephron Development
The morphological events and localization of renal progenitors occurring during nephron development in the adult human kidney.
Mesenchymal cells near the tips of the branching ureteric bud undergo epithelial transition and differentiate through a series of forms made up of renal progenitors (red)
- a - condensed aggregate forms
- b - renal vesicle forms
- c - S-shaped body (red), renal progenitors are localised, at this stage podocyte-committed progenitors (red + blue) as well as tubular-committed progenitors (orange) can already be seen.
- d - mature nephron, renal progenitors (red), podocyte-committed progenitors (red + blue), as well as tubular-committed progenitors (orange) are distributed along the nephron.
- e - glomerulus, renal progenitors (red) are localized at the urinary pole of the Bowman capsule. Podocyte-committed progenitors (red + blue) localize along the Bowman capsule.
- Links: early nephron development | Fetal nephron development | Adult nephron distribution | Renal System Development
Reference
Romagnani P, Lasagni L & Remuzzi G. (2013). Renal progenitors: an evolutionary conserved strategy for kidney regeneration. Nat Rev Nephrol , 9, 137-46. PMID: 23338209 DOI.
Copyright
Reprinted by permission from Macmillan Publishers Ltd: Nature Reviews Nephrology (Romagnani, P. et al. Nat. Rev. Nephrol. 9, 137–146 (2013); published online 22 January 2013; doi:10.1038/nrneph.2012.290), copyright (2013) License Number 3954020439682
Figure 4 resized and relabelled with PMID
Cite this page: Hill, M.A. (2024, March 19) Embryology Nephron development 01.jpg. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/File:Nephron_development_01.jpg
- © Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G
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