File:Mouse pancreas development.jpg

From Embryology
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Mouse Pancreas Development

Remodeling of the pancreatic epithelial cell mass into polarized monolayers.

  • Pancreatic sections from e10.5 to e15.5 embryos were examined by immunofluorescence using antibodies directed against E-cadherin, mucin-1 and laminin.
  • Pancreatic development starts by the formation of a mass of non-polarized epithelial cells (e10.5-e11.5).
  • This mass is then remodeled (e12.5-e13.5) and finally every epithelial cell become polarized, with its basal pole contacting laminin and its apical pole facing a lumen (e14.5-e15.5).
* indicates the central duct, in connection with the duodenum.

Scale bar, 100 μm.

Original file name: 1471-213X-9-66-1.jpg

Reference

<pubmed>20003423</pubmed>| BMC Dev Biol.

Hick et al. BMC Developmental Biology 2009 9:66 doi:10.1186/1471-213X-9-66


© 2009 Hick et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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current20:07, 9 July 2011Thumbnail for version as of 20:07, 9 July 2011600 × 939 (261 KB)S8600021 (talk | contribs)==Mouse Pancreas Development== Remodeling of the pancreatic epithelial cell mass into polarized monolayers. Pancreatic sections from e10.5 to e15.5 embryos were examined by immunofluorescence using antibodies directed against E-cadherin, mucin-1 and la
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