File:Mouse neural tube bending model.jpg

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Mouse Neural Tube Bending Model

The closing mouse spinal neural plate bends at the midline and dorsolaterally.

  • Basal nuclear localisation causes midline, but not dorsolateral, bending.
  • Neuroepithelial cells translocate into the dorsolateral neural plate during closure.
  • A discontinuity of cell density results between dorsal and ventral neural plate.
  • Buckling at this discontinuity may result in dorsolateral neural plate bending.


Links: Neural System Development | Mouse Development

Reference

<pubmed>26079577</pubmed>| PMC4528075 | Dev Biol.

Dev Biol. 2015 Aug 15; 404(2): 113–124. doi: 10.1016/j.ydbio.2015.06.003

Copyright

http://creativecommons.org/licenses/by/4.0

Image resized and PMID label added.



Cite this page: Hill, M.A. (2024, April 24) Embryology Mouse neural tube bending model.jpg. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/File:Mouse_neural_tube_bending_model.jpg

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© Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G

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current15:36, 16 August 2015Thumbnail for version as of 15:36, 16 August 20151,000 × 471 (79 KB)Z8600021 (talk | contribs)===Cellular basis of neuroepithelial bending during mouse spinal neural tube closure=== Dev Biol. 2015 Aug 15;404(2):113-24. doi: 10.1016/j.ydbio.2015.06.003. Epub 2015 Jun 12. McShane SG1, Molè MA1, Savery D1, Greene ND1, Tam PP2, Copp AJ3. Abstra...

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