File:Mouse - stomach 01.png
Morphological abnormality in the stomach of Sfrp1−/− Sfrp2−/− and Sfrp1−/− Sfrp2−/− Sfrp5+/− embryos
- Links: Full original figure | Mouse-Gastrointestinal tract E10.5 | Mouse-Gastrointestinal tract E13.5
(A–E) A small fore-stomach is formed in Sfrp1−/− Sfrp2−/− and Sfrp1−/− Sfrp2−/− Sfrp5+/− embryos at E13.5, as evidenced by expression of Shh (A), Pitx1 (B), Nkx6.3 (C), Islet1 (D) and Barx1 (E). A broken line depicts Shh-negative epithelium along the greater curvature. Curved arrows, an arrow and double arrowheads denote the fore-stomach, the junction of the esophagus and fore-stomach and the pyloric sphincter, respectively. A white arrowhead defines the caudal end of the fore-stomach. A black arrowhead indicates the rostral end of marker gene expression. Fs, fore-stomach.
Scale bar: 500 µm.
(F–I) A region of presumptive stomach and duodenum is generated normally in Sfrp1−/− Sfrp2−/− and Sfrp1−/− Sfrp2−/− Sfrp5+/− embryos at E10.5, which is suggested by the expression patterns of Shh (F), Pdx1 (G), Sfrp5 (H) and Barx1 (I). The area between the arrowheads identifies a Shh-negative region in the gut epithelium (F). Arrows depict the rostral and caudal ends of marker gene expression (G, H). Ce, cecum; Lb, lung bud; Pb, pancreatic bud; St, stomach.
Scale bar: 500 µm.
Original Image: Figure 1. Journal.pgen.1000427.g001.png
<pubmed>19300477</pubmed>| PLoS Genet.
Copyright: © 2009 Matsuyama et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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|current||12:21, 22 August 2010||599 × 600 (1.45 MB)||S8600021||==Morphological abnormality in the stomach of Sfrp1−/− Sfrp2−/− and Sfrp1−/− Sfrp2−/− Sfrp5+/− embryos== ===E13.5=== (A–E) A small fore-stomach is formed in Sfrp1−/− Sfrp2−/− and Sfrp1−/− Sfrp2−/− Sfrp5+/− embryos at|
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