File:Mouse-pituitary Sox4 expression.jpg

In situ hybridization of Sox4 in mice fetal pituitaries

A-D show the images hybridized with Sox4 probe. The positive blue color was initiated by alkaline phosphatase and BCIP/NBT.

All the slides were counterstained with 0.1% nuclear fast red after in situ hybridization.

Original magnification, ×200 (bar, 50 μm).

"The significant changes in gene expression in both tissues suggest a distinct and dynamic switch between embryonic and adult pituitaries. All these data along with Sox4 should be confirmed to further understand the community of multiple signaling pathways that act as a cooperative network that regulates maturation of the pituitary. It was also suggested that EST sequencing is an efficient means of gene discovery."

Original file name: Figure 3. 1471-2164-10-109-3.jpg http://www.biomedcentral.com/1471-2164/10/109/figure/F3

Reference

http://www.biomedcentral.com/1471-2164/10/109

Ma et al. BMC Genomics 2009 10:109 doi:10.1186/1471-2164-10-109

© 2009 Ma et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.