File:Mouse-pancreas islets-sweet taste receptor.jpg
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Expression of T1R3 in Islets
Mouse islets expressed T1R2 and T1R3, and artificial sweeteners stimulated insulin secretion. The sweet taste receptor is a heterodimer of T1R2 and T1R3, both of which belong to a subclass of G-protein-coupled receptors resembling metabotropic glutamate receptor (mGluR), calcium-sensing receptor and pheromone receptors (V2R).
Pancreatic slices were stained with anti-T1R3 (a) and anti-insulin (b) antibodies. c: merge.
Reference
<pubmed>19352508</pubmed>| PMC2663034
Copyright Nakagawa et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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| current | 13:06, 30 September 2010 | | 1,050 × 261 (38 KB) | S8600021 (talk | contribs) | ==Expression of T1R3 in Islets== Mouse islets expressed T1R2 and T1R3, and artificial sweeteners stimulated insulin secretion. The sweet taste receptor is a heterodimer of T1R2 and T1R3, both of which belong to a subclass of G-protein-coupled receptors re |
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