File:Morphological differences in early mouse embryonic development.png

Schematic view of morphological and lineage specification steps during the early mouse embryonic development

Starting from fertilization (E0), after three rounds of cleavages (E1–E2.5), the blastomers undergo compaction and polarization (E3). Then the trophectoderm outer layer starts to separate from the inner cell mass (ICM) followed by the expansion of the blastocoel and the localization of the ICM to one part of the embryo (E3.5). After this stage the endoderm is formed as a layer separating epiblast from blastocoel (E4.5). After 4.5 embryonic days, the preimplantation embryo contains more than 100 cells. http://dx.doi.org/10.1371/journal.pcbi.1001128.g001

Reference

<pubmed>PMC3088645</pubmed> Copyright

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