File:Meiotic chromosome crossovers 01.jpg

Diagram depicting meiotic crossovers in regions along a chromosome

The p and q arms of the chromosome are divided into 10% intervals, with the centromere (C) at 0%, and telomeres at 100%.

The subtelomere is shaded in the 80–100% intervals.

The pericentromere, the region surrounding the centromere is shaded in the 10–30% intervals.

This region attracts high levels of cohesin which are protein complexes that hold sister chromatids together until they separate during meiosis.

Crossover formation in each region of the chromosome, and the resulting recombinant chromosomes are illustrated:

a) a single crossover near the telomere on the p-arm;

b) a single crossover near the centromere on the q-arm;

c) a single crossover near the telomere on the q-arm;

d) double crossovers on the q-arm.

Links: meiosis

Reference

Ren H, Ferguson K, Kirkpatrick G, Vinning T, Chow V & Ma S. (2016). Altered Crossover Distribution and Frequency in Spermatocytes of Infertile Men with Azoospermia. PLoS ONE , 11, e0156817. PMID: 27273078 DOI.

Copyright

© 2016 Ren et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Fig 2. https://doi.org/10.1371/journal.pone.0156817.g002 Original figure altered in size and labeled with reference PMID.

Cite this page: Hill, M.A. (2024, April 19) Embryology Meiotic chromosome crossovers 01.jpg. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/File:Meiotic_chromosome_crossovers_01.jpg

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© Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G