File:Lymph node structure 02.jpg
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Lymph Node Structure
Schematic representation of the organization of a lymph node.
- Afferent lymphatics enter lymph nodes and deliver lymph to the subcapsular sinus (SCS), which forms a channel around the periphery of the lymph node.
- Lymphatic sinuses run from the SCS through the cortex to the medulla
- Efferent lymphatics exit the lymph node via efferent lymphatic vessels on the opposite (hilar) side of the organ.
- High endothelial venules (HEVs) - in the paracortex and cortical ridge, specialized vessels allow entry of leukocytes from the blood.
- Blood vessels enter and exit the lymph node on the hilar side, and snake through the lymph node like the branches of a tree.
- B cell follicles containing follicular dendritic cell (FDC) networks are arranged in the lymph node cortex and are separated from the SCS by a layer of marginal reticular cells (MRC).
- T cells zones in the paracortex, which contain many fibroblastic reticular cells (FRC), are separated by the cortical ridge, an area rich in T cells, dendritic cells (DCs), blood vessels, and FRC.
Scale bars represent 200 μM.
- Lymph Node Cartoons: Detailed structure | Cartoon with Histology | Lymphocyte traffic | Simple structure | Simple node anatomy | Wiki node image | Internal structure | Mesenteric lymph node | Histology | Gallery | Lymph Node Development
Reference
Mueller SN & Germain RN. (2009). Stromal cell contributions to the homeostasis and functionality of the immune system. Nat. Rev. Immunol. , 9, 618-29. PMID: 19644499 DOI. Mueller
Copyright
Cite this page: Hill, M.A. (2024, April 24) Embryology Lymph node structure 02.jpg. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/File:Lymph_node_structure_02.jpg
- © Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 18:53, 22 February 2012 | | 460 × 463 (54 KB) | Z8600021 (talk | contribs) | ==Lymph node structure== Schematic representation of the organization of a lymph node (left panel). Afferent lymphatics enter lymph nodes and deliver lymph to the subcapsular sinus (SCS), which forms a channel around the periphery of the lymph node. Lymp |
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