File:Lung bud.png

The Expression of Tbx4 and Tbx5 in the developing lung and trachea

The red arrows point out the posterior part of the third pharyngeal pouch. Tbx4 is first expressed at E9.5 along with Tbx5 in the newly formed lung buds (E,F).Expression is seen in lung whole mounts at E11.5 (G,H).

I do acknowledge that this image is not the original, and that it ha been edited by cutting out the bottom half. Isolating the top half of the real image and focusing on the external features of the lung.

Copyright

Copyright Arora et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Reference

Metters KM, Rossier J, Paquin J, Chrétien M & Seidah NG. (1988). Selective cleavage of proenkephalin-derived peptides (less than 23,300 daltons) by plasma kallikrein. J. Biol. Chem. , 263, 12543-53. PMID: 3410851

|PubMed:The Expression of Tbx4 and Tbx5 in the developing lung and trachea.

--Mark Hill (talk) 11:26, 7 November 2014 (EST) Assessment - This is a good molecular development image, but you have not taken the opportunity to explain the roles of these factors. Your pubmed link is to the wrong reference and the copyright info should be beneath the reference. PMID 22876201 I have shown the correct reference info below. The fact that it is still here means that you have not checked your work correctly, I found the correct ref by simply searching with "The expression of Tbx4 and Tbx5 in the developing lung and trachea." The file name is both inappropriate and also misspelt and this should have been fixed by reuploading and notifying me to delete.

Arora R, Metzger RJ & Papaioannou VE. (2012). Multiple roles and interactions of Tbx4 and Tbx5 in development of the respiratory system. PLoS Genet. , 8, e1002866. PMID: 22876201 DOI.

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