File:Fragile X protein ISO6 and Cajal bodies.jpg

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Fragile X protein ISO6 and Cajal bodies

Localization of nuclear FMRP isoforms tagged with GFP, after transfection of HeLa cells with the corresponding expression vectors.

Note the presence of ISO6 and ISO12 in Cajal bodies. GFP-ISO6 FMRP colocalizes with Coilin in Cajal bodies (white arrow heads).


Links: Image - FMRP and Cahal bodies | FMRP model | Fragile X Syndrome | Cajal


Reference

Dury AY, El Fatimy R, Tremblay S, Rose TM, Côté J, De Koninck P & Khandjian EW. (2013). Nuclear Fragile X Mental Retardation Protein is localized to Cajal bodies. PLoS Genet. , 9, e1003890. PMID: 24204304 DOI.

Copyright

© 2013 Dury et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Figure 4 doi:10.1371/journal.pgen.1003890.g004 panel C cropped from full figure. Resized and relabelled.


Cite this page: Hill, M.A. (2024, April 24) Embryology Fragile X protein ISO6 and Cajal bodies.jpg. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/File:Fragile_X_protein_ISO6_and_Cajal_bodies.jpg

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© Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G

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current10:05, 15 August 2014Thumbnail for version as of 10:05, 15 August 20141,000 × 397 (41 KB)Z8600021 (talk | contribs)===Nuclear Fragile X Mental Retardation Protein is localized to Cajal bodies=== PLoS Genet. 2013 Oct;9(10):e1003890. doi: 10.1371/journal.pgen.1003890. Epub 2013 Oct 31. Dury AY1, El Fatimy R, Tremblay S, Rose TM, Côté J, De Koninck P, Khandjian EW....

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