File:Cytotrophoblast to syncytiotrophoblast cartoon.png
Cytotrophoblast_to_syncytiotrophoblast_cartoon.png (600 × 385 pixels, file size: 242 KB, MIME type: image/png)
Human villous cytotrophoblast (CTB) cells to a syncytiotrophoblast (STB) phenotype
Schematic representation for the role of NR2F2 in the differentiation of human villous human villous cytotrophoblast (CTB) cells to a syncytiotrophoblast (STB) phenotype.
- NR2F2 transactivates the TFAP2A promoter and potentiates the transactivation of the promoter by RARA and RXRA.
- Activation of TFAP2A in turn modulates the expression of downstream genes involved in terminal STB cell differentiation.
Original file name: Figure 8. Journal.pone.0009417.g008.png http://www.plosone.org/article/slideshow.action?uri=info:doi/10.1371/journal.pone.0009417&imageURI=info:doi/10.1371/journal.pone.0009417.g008
Reference
<pubmed>20195529</pubmed>| PLoS One
Copyright: © 2010 Hubert et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
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| current | 00:14, 13 October 2010 | | 600 × 385 (242 KB) | S8600021 (talk | contribs) | ==Schematic representation for the role of NR2F2 in the differentiation of human villous human villous cytotrophoblast (CTB) cells to a syncytiotrophoblast (STB) phenotype== NR2F2 transactivates the TFAP2A promoter and potentiates the transactivation of |
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