File:Chromosome telomeres.jpg

From Embryology

Chromosome_telomeres.jpg(600 × 471 pixels, file size: 33 KB, MIME type: image/jpeg)

Chromosome Telomeres

Telomeres are shown fluorescently labeled (white dots) at ends of chromosome pairs in a metaphase spread.

Telomeres

Genetic and cell biology term referring to the regions found at the ends of each chromosome and involved in cellular ageing and the capacity for division. The regions consist of repeated sequences protecting the ends of chromosomes and harbour DNA repair proteins. In the absence of the enzyme telomerase, these regions shorten during each cell division and becoming critically short, cell senescence occurs.

Not on bacterial DNA (circular), proposed to provide each cell with a replication counting mechanism that helps prevent unlimited proliferation, each cell division shortens telomere 50–100 nucleotides, DNA 100s to 1,000s repeats of a simple-sequence containing clusters of G residues (humans AGGGTT), Telomerase enzyme maintains length.


Links: Cell Division - Mitosis | Cell Division - Meiosis | Image - Early human telomeres | Image - Early human telomere length)

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current11:49, 25 October 2010Thumbnail for version as of 11:49, 25 October 2010600 × 471 (33 KB)S8600021 (talk | contribs)==Chromosome Telomeres== Telomeres are shown fluorescently labeled (white dots) at ends of chromosome pairs in a metaphase spread. ===Telomeres=== Genetic and cell biology term referring to the regions found at the ends of each chromosome and involved

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