File:Abnormal formation of fertilisation cones .jpg

Heparin induces polyspermy and abnormal formation of fertilization cones

Formation of the fertilization cone was monitored in living eggs after sperm addition. (A) F-actin was visualized by microinjection of fluorescent phalloidin. (B) Transmission photomicrographs of the same eggs. Both phalloidin-stained actin networks and the transmission photomicrographs displayed formation of single and round fertilization cone (arrow) in the control egg by 9 min after adding sperm. In contrast, heparin-treated eggs displayed abnormal formation of multiple and piriform-shaped fertilization cones (arrowheads).

(Original figure legend, image based on data PMID 18974786)

Reference

<pubmed>18974786</pubmed>|[1]

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