Category:Mouse E14

From Embryology

This Embryology category shows pages and media related to embryonic day 14 E14.0 of mouse development.

This staging by "days" relate to in the female presence of a vaginal plug indicating that the mating occurred, see timed pregnancy.


Mouse Stages: E1 | E2.5 | E3.0 | E3.5 | E4.5 | E5.0 | E6.0 | E7.0 | E7.5 | E8.0 | E8.5 | E9.0 | E9.5 | E10 | E10.5 | E11 | E11.5 | E12 | E12.5 | E13 | E13.5 | E14 | E14.5 | E15 | E15.5 | E16 | E16.5 | E17 | E18.5 | E18 | E18.5 | E19 | E20 | Timeline | About timed pregnancy


Species Embryonic Comparison Timeline
Carnegie Stage
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
Human Days 1 2-3 4-5 5-6 7-12 13-15 15-17 17-19 20 22 24 28 30 33 36 40 42 44 48 52 54 55 58
Mouse Days 1 2 3 E4.5 E5.0 E6.0 E7.0 E8.0 E9.0 E9.5 E10 E10.5 E11 E11.5 E12 E12.5 E13 E13.5 E14 E14.5 E15 E15.5 E16
Rat Days 1 3.5 4-5 5 6 7.5 8.5 9 10.5 11 11.5 12 12.5 13 13.5 14 14.5 15 15.5 16 16.5 17 17.5
Note these Carnegie stages are only approximate day timings for average of embryos. Links: Carnegie Stage Comparison
Table References  
Human

O'Rahilly R. (1979). Early human development and the chief sources of information on staged human embryos. Eur. J. Obstet. Gynecol. Reprod. Biol. , 9, 273-80. PMID: 400868

Mouse
Theiler K. The House Mouse: Atlas of Mouse Development (1972, 1989) Springer-Verlag, NY. Online
OTIS EM & BRENT R. (1954). Equivalent ages in mouse and human embryos. Anat. Rec. , 120, 33-63. PMID: 13207763

Rat
Witschi E. Rat Development. In: Growth Including Reproduction and Morphological Development. (1962) Altman PL. and Dittmer DS. ed. Fed. Am. Soc. Exp. Biol., Washington DC, pp. 304-314.
Pérez-Cano FJ, Franch À, Castellote C & Castell M. (2012). The suckling rat as a model for immunonutrition studies in early life. Clin. Dev. Immunol. , 2012, 537310. PMID: 22899949 DOI.

Timeline Links: human timeline | mouse timeline | mouse detailed timeline | chicken timeline | rat timeline | Medaka | Category:Timeline
mouse

Events

  • Salivary Gland Development - simple one-bud one-duct salivary gland has both grown and branched significantly, and the main duct begins to lumenize. The end buds undergo reorganization and begin to form acini – the main secretory units of the salivary gland. [1]
  • Integumentary System Development - Ectodysplasin receptor (EDAR) expressed in the epidermis basal cells and hair placodes.[2]
    • Hair Development - a primary wave of hair follicle placode induction takes place, these primary hairs only form 2% of the adult hair population and are associated with touch domes. Secondary (E16) and tertiary (E18) waves of hair follicle induction are responsible for forming the three remaining types of hair follicles.[3]
    • Nail Development - primordial nails (claws) begin to appear on the dorsal surface of the developing distal digits of mouse limbs between E14 to E15, [4]
  • Pancreas - day 13 to 14 (E13, E13.5, E14) stomach rotation brings the smaller ventral pancreatic bud dorsally to fuse with the larger dorsal pancreatic bud.
  • Palate Development - palatal shelves become elevated horizontally above the tongue.

References

  1. Melinda Larsen, Kenneth M Yamada, Kurt Musselmann Systems analysis of salivary gland development and disease. Wiley Interdiscip Rev Syst Biol Med: 2010, 2(6);670-82 PubMed 20890964
  2. M Yan, L C Wang, S G Hymowitz, S Schilbach, J Lee, A Goddard, A M de Vos, W Q Gao, V M Dixit Two-amino acid molecular switch in an epithelial morphogen that regulates binding to two distinct receptors. Science: 2000, 290(5491);523-7 PubMed 11039935
  3. Olivier Duverger, Maria I Morasso Epidermal patterning and induction of different hair types during mouse embryonic development. Birth Defects Res. C Embryo Today: 2009, 87(3);263-72 PubMed 19750518
  4. Chang-Yi Cui, Joakim Klar, Patrik Georgii-Heming, Anne-Sophie Fröjmark, Shahid M Baig, David Schlessinger, Niklas Dahl Frizzled6 deficiency disrupts the differentiation process of nail development. J. Invest. Dermatol.: 2013, 133(8);1990-7 PubMed 23439395

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Pages in category ‘Mouse E14’

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Media in category ‘Mouse E14’

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