Category:Mouse E12.5

From Embryology

The Embryology pages and media listed below relate to mouse embryonic day 12.5 E12.5 of development. This staging by "days" relate to in the female presence of a vaginal plug indicating that the mating occurred, see timed pregnancy.

Mouse Stages: E1 | E2.5 | E3 | E3.5 | E4.5 | E5.0 | E6.0 | E7.0 | E7.5 | E8.0 | E8.5 | E9.0 | E9.5 | E10 | E10.5 | E11 | E11.5 | E12 | E12.5 | E13 | E13.5 | E14 | E14.5 | E15 | E15.5 | E16 | E16.5 | E17 | E17.5 | E18 | E18.5 | E19 | E20 | Timeline | About timed pregnancy


Species Stage
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
Human Days 1 2-3 4-5 5-6 7-12 13-15 15-17 17-19 20 22 24 28 30 33 36 40 42 44 48 52 54 55 58
Mouse Days 1 2 3 4 5.0 6.0 7.0 8.0 9.0 9.5 E10 10.5 11 11.5 12 12.5 13 13.5 14 14.5 15 15.5 16
Rat Days 1 3.5 4-5 5 6 7.5 8.5 9 10.5 11 11.5 12 12.5 13 13.5 14 14.5 15 15.5 16 16.5 17 17.5
Note these Carnegie stages are only approximate day timings for average of embryos. Links: Carnegie Stage Comparison
References  
Human

R O'Rahilly Early human development and the chief sources of information on staged human embryos. Eur. J. Obstet. Gynecol. Reprod. Biol.: 1979, 9(4);273-80 PubMed 400868


Mouse
The House Mouse: Atlas of Mouse Development by Theiler Springer-Verlag, NY (1972, 1989). | online book
E M OTIS, R BRENT Equivalent ages in mouse and human embryos. Anat. Rec.: 1954, 120(1);33-63 PubMed 13207763


Rat
Witschi, E. (1962) Development: Rat. In: Growth Including Reproduction and Morphological Development. Altman, P. L. , and D. S. Dittmer, ed. Fed. Am. Soc. Exp. Biol., Washington DC, pp. 304-314.
Francisco J Pérez-Cano, Àngels Franch, Cristina Castellote, Margarida Castell The suckling rat as a model for immunonutrition studies in early life. Clin. Dev. Immunol.: 2012, 2012;537310 PubMed 22899949

Mouse Links: Introduction | Mouse Stages | Mouse Timeline | Mouse Timeline Detailed | Mouse Estrous Cycle | Mouse Heart | Mouse Knockout | Movie - Cephalic Plexus | Movie - Blastocyst Cdx2 | ANAT2341 Project (2009) | Category:Mouse
Mouse Movies 
Mouse Zygote  
Fertilization 001 icon.jpg
 ‎‎Mouse Fertilisation
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Mouse zygote division icon.jpg
 ‎‎Zygote Mitosis
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Mouse zygote division 02 icon.jpg
 ‎‎Early Division
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Parental genome mix 01 icon.jpg
 ‎‎Parental Genomes
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Mouse blastocyst movie icon.jpg
 ‎‎Mouse Blastocyst
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Mouse Various  
Oocyte Meiosis 01 icon.jpg
 ‎‎Oocyte Meiosis
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DNA bead-induced ectopic polar body-icon.jpg
 ‎‎Ectopic Polar Body
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Mouse spermatozoa mito movie icon.jpg
 ‎‎Male Mitochondria
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Mouse spermatozoa mito movie icon.jpg
 ‎‎Male Mitochondria
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Mouse Blastocyst Cdx2 icon.jpg
 ‎‎Blastocyst Cdx2
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Model embryo to 128 cell stage icon.jpg
 ‎‎Blastocyst Model
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Mouse lipid droplets icon.jpg
‎‎Mouse Lipid Drops
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Somitogenesis 01 icon.jpg
 ‎‎Somitogenesis
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Mouse-melanoblast migration icon.jpg
 ‎‎Mouse Melanoblast
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Mouse limb gene expression icon.jpg
 ‎‎Limb Genes
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Mouse microCT  
Mouse CT E11.5 movie-icon.jpg
 ‎‎Mouse E11.5 CT
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Mouse CT E12.5 sagittal movie.jpg
 ‎‎Mouse E12.5 CT
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Mouse CT E12.5 coronal movie.jpg
 ‎‎Mouse E12.5 CT
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Mouse CT E12.5 axial movie.jpg
 ‎‎Mouse E12.5 Axial
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Mouse embryo E13 microCT icon.jpg
 ‎‎Mouse E13 microCT
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Mouse embryo E14 microCT icon.jpg
 ‎‎Mouse E14 microCT
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Mouse embryo E14 sectioned microCT icon.jpg
 ‎‎Mouse E14 microCT
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Mouse embryo E15 microCT icon.jpg
 ‎‎Mouse E15 microCT
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Mouse face microCT icon.jpg
 ‎‎Mouse Face
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Mouse-Cephalic-plexus-11somite 01.jpg
 ‎‎Mouse Head Plexus
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Historic Embryology - Mouse 

Events

  • Musculoskeletal System - Abdominal wall second body wall region containing myoblasts thicker (780 μm) than the primary body wall (180 μm). Now distinct inner and outer layers of tissue: inner layer shows unidirectional cell orientation; outer layer has no orientation.[1]
  • Palate Development - secondary palatal development begins. E12.5 to E14 grow vertically along the developing tongue.
  • Salivary Gland Development - indentations (clefts) start to form on the surface of the epithelial bud accompanied by alterations in the basement membrane. Clefts separate the primary bud into multiple buds and the epithelium proliferates. The base of the cleft becomes the primordial ductal structure, salivary branching morphogenesis is repeated multiple times over the following days.[2]
  • Cardiovascular - Haematopoietic stem cells (HSCs) appear in the fetal liver.[3]


References

  1. Peter F Nichol, Robert F Corliss, Shigehito Yamada, Kohei Shiota, Yukio Saijoh Muscle patterning in mouse and human abdominal wall development and omphalocele specimens of humans. Anat Rec (Hoboken): 2012, 295(12);2129-40 PubMed 22976993 | PMC3976953 | Anat Rec (Hoboken)
  2. Melinda Larsen, Kenneth M Yamada, Kurt Musselmann Systems analysis of salivary gland development and disease. Wiley Interdiscip Rev Syst Biol Med: 2010, 2(6);670-82 PubMed 20890964
  3. Stanislav Rybtsov, Andrejs Ivanovs, Suling Zhao, Alexander Medvinsky Concealed expansion of immature precursors underpins acute burst of adult HSC activity in foetal liver. Development: 2016, 143(8);1284-9 PubMed 27095492

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Pages in category ‘Mouse E12.5’

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Media in category ‘Mouse E12.5’

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