Category:Carnegie Stage 16

From Embryology

This Embryology category shows pages and media related to embryonic development in week 6, 37 - 42 days, GA week 8. The embryos have a crown rump length (CRL) of 8 - 11 mm. Stage 16 and 17 are the only two stages occurring in week 6 of the historic 23 Carnegie stages of embryonic development.


There is also a specific Carnegie stage 16 resource page. See also Carnegie Stage 16 - Events

Stage 16 Links: Week 6 | Head | Lecture - Limb | Lecture - Gastrointestinal | Lecture - Head Development | Science Practical - Gastrointestinal | Science Practical - Head | Carnegie Embryos | Category:Carnegie Stage 16 | Week 6 | Next Stage 17
  Historic Papers: 1906 | 1908 | 1948 stages 15-18
Week: 1 2 3 4 5 6 7 8
Carnegie stage: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23


Carnegie Collection - Stage 16 
Serial No. Size (mm) Grade Fixative Embedding Medium Plane Thinness (µm) Stain Year Notes
163 E., 9.0 Ch., 35x35x20 Good Formol P Transverse 20 Al. coch. 1899 Used by Bardeen and Lewis
221 E., 7.5 Ch., 40x33x33 Poor Formol P Sagittal 20 Al. coch. 1903 Macerated
383 E., 7.0 Ch., 15x15x15 Poor Formol P Transverse 10 Al. carm., H. & Congo red 1904
397 E., 8.0 Ch., 15x15x15 Poor Formol P Transverse 10 (Stain - Haematoxylin Eosin) 1907
422 E., 9.0 Ch., 30x30x30 Poor Alc. P Transverse 40 Al. coch. 1910 Tubal. Partly macerated
559 E., 8.6 Ch., 20x15x12 Good Formol P Transverse 20 H. & Congo red 1911 Cyclopia. Formerly listed as stage 17
589 E., 11 Ch., 30x13x13 Poor p P Sagittal 50 Al. coch. 1912
617 E., 7.0 Ch., 18x14x12 Good Formol P Transverse 15 Al. coch. 1912 Median in group
636 E., 10 Ch.,28x28x22 Poor Formol P Transverse 50 Al. coch. 1913 Macerated
651f E., 7 Ch., 25x20x15 Poor p p p p p 1913 Spina bifida
675 E., 10 Ch., 50x30x25 Poor Formol P Sagittal 100 Carmine 1915 Abnormal head and limbs
792 E., 8.0 Ch., 40x30x30 Good Formol P Transverse 20 Al. coch. 1913 Advanced
887 E, 9.0 Ch., 31x28x17 Good Formol P Transverse 40 Al. coch. 1914 Near next stage
1121 E., 11.8 Good Corros. acetic P Coronal 40 Al. coch. 1915 Operative. Median in group
1197 E., 10.0 Ch., 23x19x15 Good Formol C Sagittal 20 (Stain - Haematoxylin Eosin), or. G. 1915 Advanced
1544 E., 7.2 Good Zenker P Sagittal 20 Al. coch. 1916 Tubal. Mechanical injury
1836 E., 11.0 Good Formol P Transverse 20 (Stain - Haematoxylin Eosin) 1917 Most-advanced third
4677 E., 9.5 Ch., 48x36x30 Good Formol P Transverse 10 Al. coch. 1924 Median in group
5515 E., 12.0 Ch., 47x37x25 Good Formol C-P Transverse 10 (Stain - Haematoxylin Eosin) 1927 Near next stage
6054 E., 7,0 Ch., 21x17x12 Good Formol C-P Transverse 8 (Stain - Haematoxylin Eosin) 1930 Least-advanced third
6507 E., 9.0* Excellent Corros. acetic C-P Coronal 10 & 8 Al. coch. p Middle or most-advanced third
6509 E. 8.1* Excellent Corros. acetic C-P Coronal 10 Al. coch. p Least-adianced or middle third
6510 E., 10.1* Excellent Corros. acetic C-P Coronal 10 Al. coch. p Close to No. 6507. Ag added
6511 E, 8.1* Good Corros. acetic C-P Sagittal 10 Al. coch., iron H. p Surface injured by fixative. Most-advanced third
6512 E., 7.0* Excellent Corros. acetic C-P Transverse 10 Al. coch. p Least-advanced third. Borderline
6513 E., 7.2* Good Corros. acetic C-P Coronal 10 Al. coch. p Surface injured by fixative. Least advanced in group
6514 E, 9 0* Poor Corros. acetic C-P Sagittal 10 Al. coch. p Most-advanced third
6516 E., 10 5* Good Corros acetic C-P Sagittal 8 Al. coch. p Most-advanced third. Double left kidney and ureter
6517 E., 10.5* Excellent Corros. acetic C-P Transverse 8 Al. coch.  ? Close to No. 6516
6686 E., 11.0 Ch., l7x17xP Poor Formol C-P Coronal 20 Al. coch. 1933 Tubal. Partly macerated
6750 E., 10.0 Good Formol C-P Transverse 10 H. & phlox. 1933 Tubal. Advanced
6909 E., 11.0 Good Bouin C-P Coronal 10 (Stain - Haematoxylin Eosin) 1934 Tubal. Advanced
6931 E., 8.8 Ch., 3""x 33x16 Good Formol C-P Coronal 10 Al coch., phlox. 1934 Least-advanced third. Type specimen
6950 E.. 9 0 Ch., 3lx20x18 Good Formol C-P Transverse 10 (Stain - Haematoxylin Eosin) 1934 Tubal. Partly fragmented
7?15 E., 9.7 Exc Bouin C-P Coronal 10 H. & phlox 1935 Operative. Less advanced
7629 E., 11.5 Ch., 31x31 Good Formol C-P Coronal 10 Al. coch., phlox 1939 Hysterectomy. Most advanced in group
7804 E., 9.5 Ch., 26x21x16 Good Formol C-P Transverse 10 (Stain - Haematoxylin Eosin) 1940 Least-advanced third
7897 E., 12.2 Ch., 31x24x23 Good Formol C-P Transverse 10 (Stain - Haematoxylin Eosin) 1941 Tubal. Advanced
8098 E., 10.0 Ch., 30 Good Formol C-P Coronal 6 (Stain - Haematoxylin Eosin) 1942 Tubal. Median in group
8112 E., 10.9 Excellent Bouin C-P Coronal 8 (Stain - Haematoxylin Eosin) 1943 Most-advanced third
8179 E., 11.9 Ch., 23x18x17 Good Formol C-P Coronal 10 (Stain - Haematoxylin Eosin) 1943 Tubal
8436 E., 10.9 Ch., 13x15x1? Good Formol P Coronal 10 Azan 1946 Advanced
8692 E., 10 Good Bouin P Transverse 10 (Stain - Haematoxylin Eosin) 1949 Rubella. Medical abortion. Mechanically damaged
8697 E., 11.3 Poor Formol C-P Transverse 10 (Stain - Haematoxylin Eosin) 1949 Perhaps stage 17
8773 E, 11 Excellent Bouin P Coronal 10 Azan 1950
Template:CE8971 E., 10 Ch., 20.5x14.5x13.7 Poor Formol Transverse 15 (Stain - Haematoxylin Eosin) 1932 Synophthalmia. Univ. Chicago No. H 1439
Template:CE9055 E., ca. 10 Excellent Bouin P Transverse 20 Azan & Ag 1953 Damaged
Template:CE9229 E, 9.5 Excellent Formol P Transverse 6 Ag & (Stain - Haematoxylin Eosin) 1954 Stage 15, 16, or 17? Mislaid
Abbreviations
  • Size - E. is the greatest length of the embryo and Ch. is the mean diameter of the chorion.
  • Grade - total grade of the specimen and includes both its original quality and the condition of the mounted sections.
  • Embedding medium - paraffin (P) or a combination of celloidin and paraffin (C-P).
  • Fixative - formalin (Formol), alcohol and formalin (Alc, formol), Bouin Bouin solution)
  • Stain -
  •  ? - unknown or not determined.
Madrid Collection - Stage 16  
Carnegie
Stage
Embryo Days CRL (mm) Section
thickness
Staining Section plane
16 MAR 3 38 8 10 (Stain - Haematoxylin Eosin)-Azan frontal
16 BOT9 39 9 10 (Stain - Haematoxylin Eosin) transverse
16 CN 2 39 9.5 10 (Stain - Haematoxylin Eosin) sagittal
16 FAUS 4 40 9.7 10 (Stain - Haematoxylin Eosin) frontal
16 CA 2 40 10 10 (Stain - Haematoxylin Eosin)-Azan transverse
16 FE 1 40 10.5 10 (Stain - Haematoxylin Eosin) transverse


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Embryo Examples

  • No. BR, 9.75 mm G. L., 8.8 mm. Summarized by Tandler (1907)[1], who, on the basis of the coital history, gave the age as the “38th day.” About stage 16.
  • 9-mm embryo. The peripheral nervous system was described by Masy (1955)[2] in this embryo of stage 16.
  • Huber No. 3, 10 mm. The nuclei of origin of the cranial nerves and the peripheral nervous system were described by Streeter (1908a,b).[3][4] An advanced example of stage 16.
  • Wetzel (We) embryo, 10 mm. Discussed by v. Hayek (1934)[5] in regard to age, which, based on the coital history, was given as the “40th day.” Probably about stage 16.
  • Carnegie No. 6516, 10.5 mm (corrected). Double ureters described by Wharton (1949)[6].
  • No. H60, University of Missouri, 11 mm. Described briefly by Bonnot and Severs (1906).[7] Probably belongs to stage 16.


References

  1. Tandler, J. 1907. Ueber einen menschlichen Embryo vom 38. Tage. Anat. Ariz., 31. 49-56.
  2. Masy, S. 1955. Le systeme nerveux peripherique cranien de l'embryon humain de 9 mm. J. Embryol. Exp. Morphol, 3, 30-43.
  3. Streeter, G. L. 1908a. The nuclei of origin of the cranial nerves in the 10 mm human embryo. Anat. Rec, 2, 111-115.
  4. Streeter, G. L. 1908b. The peripheral nervous system in the human embryo at the end of the first month (10 mm). Amer. J. Anat., 8, 285-301.
  5. v. Hayek, H. 1934. Ein menschlicher Embryo vom 40. Tage. Anat. Anz., 78, 315-320.
  6. L R WHARTON Double ureters and associated renal anomalies in early human embryos. Contrib Embryol: 1949, 33(213-221);103-12 PubMed 18130385
  7. Bonnet E. and Severs R. On the structure of a human embryo eleven millimeters in length. (1906) Anat. Anz., 29: 452-459.

Pages in category ‘Carnegie Stage 16’

The following 67 pages are in this category, out of 67 total.

Media in category ‘Carnegie Stage 16’

The following 93 files are in this category, out of 93 total.