Category:Carnegie Embryo 790

From Embryology

Carnegie embryo first described by Mall in 1915 survey of Carnegie Collection[1]

Normal Embryos Over 9 mm Long

"There are three good specimens with embryos, ranging around 25 mm., in which the implantation of the ovum can be studied to advantage. The first (No. 790) contains what may be regarded as a normal embryo about 20 mm. long. This specimen was no doubt alive at the time of the operation, and its surface had been attached to the side of the embryonic cavity by means of a stitch. The attachment of the umbilical cord had not been destroyed, so that it was relatively easy to get suitable serial sections. The wall of the cavity is somewhat hemorrhagic; it contains numerous hyaline necrotic patches and has attached to it the tips of the villi. There is a marked inflammatory reaction. The villi of the chorion are fibrous and tipped off with trophoblast, which often form masses with necrotic cores. The trophoblast enters the tube wall and there is diffused among the muscle bundles. It often encircles and permeates the venous sinuses. The accompanying strands of cells show a considerable amount of hyaline degeneration, which gives to the sections a cartilaginous appearance. Here we have a peculiar attachment of the trophoblast without any marked intervillous hemorrhage."


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