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UNSW Embryology

Development Week by Week

© Dr Mark Hill (2008)

Acknowledgements

Introduction

This page is organised to show week by week human development features and approximate timing of key events. The "weeks" refer to embryonic development and differ from clinical weeks (shown in brackets, from last menstrual period) and "stages" refer to Carnegie stages of development. The pull down menus below will take you to specific features and the small images are linked to pages with more specific information (More? week by week detail)

Week -2

(Clinical Week 1)

Day

Menstrual cycle

Event

1

Menstrual Phase


Menstrual cycle changes: Uterine endometrium (loss), Ovary (Follicle Development)

2

 

3

   

4

   

5

Proliferative Phase


Menstrual cycle changes: Uterine endometrium (proliferation), Ovary (Follicle Development)

6

7

   

Week -1

(Clinical Week 2)

Day

 

Event

8

Proliferative Phase

9

 


Mid proliferative

10

   

11

   

12

   

13

 


Late Proliferative

14

Ovulation

Human Egg

Week 1

(Clinical Week 3)

Day

Stage

Event

1

Secretory Phase
Stage 1


Fertilization, Secretory Phase

2

Stage 2


Morula, Blastula

3

 

4

Stage 3

Blastocyst Hatching (zona pellucida lost)

5

 


Blastocyst (free floating)

6

Stage 4

Adplantation

7

Stage 5

Week 2

(Clinical Week 4)

Day

Stage

Event

8


Implantation

9

   

10

   

11

   

12

   

13

Stage 6

14

   

Week 3

(Clinical Week 5)

Day

Stage

Event

15

16

Stage 7

17

   

18

Stage 8

19

  Stage8sem

20

Stage 9

21

   

Week 4

(Clinical Week 6)

Day

Stage

Event

22

Stage 10

23

 

Heart tube "beating"

24

Stage 11

25

Stage 12

26

   

27

   

28

Stage 13

Week 5

(Clinical Week 7)

Day

Stage

Event

29

30

   

31

   

32

Stage 14

33

Stage 15

34

 

35

   

Week 6

(Clinical Week 8)

Day

Stage

Event

36

37

Stage 16

38

   

39

   

40

   

41

Stage 17

42

   

Week 7

(Clinical Week 9)

Day

Stage

Event

43

44

Stage 18

45

   

46

   

47

   

48

Stage 19

49

   

Week 8

(Clinical Week 10)

Day

Stage

Event

50

Stage 20

51

   

52

Stage 21

53

   

54

Stage 22

55

 

56

Stage 23

Week 9

(Clinical Week 11)

Day

Stage

Event

57

Fetal Period

58

   

59

 

60

   

61

 

62

   

63

 

Week 10

(Clinical Week 12)

Day

Stage

Event

64

Pancreas – insulin secretion begins.

65

   

66

 

67

   

68

 

69

   

70

 

Week 11

(Clinical Week 13)

Day

Stage

Event

71

Thyroid Gland - colloid appearance in thyroid follicles, iodine and thyroid hormone (TH) synthesis.

72

   

73

 

74

   

75

 

76

   

77

 

Second Trimester

(Clinical Week 14)

Week

Stage

Event

12

Clinical second trimester

13

   

14

15

 

Week 15 – glucagon detectable in fetal plasma

16

 

17

   

18

 

19

   

20

   

21

   

22

   

23

   

24

   

25

 

Respiratory - end month 6 alveolar cells type 2 appear and begin to secrete surfactant

Third Trimester

(Clinical Week 28)

Week

Stage

Event

26

Clinical third trimester

27

 

28

 

Respiratory - month 7 respiratory bronchioles proliferate and end in alveolar ducts and sacs

29

 

30

   

31

 

32

   

32

   

34

   

35

   

36

 

37

   

38

Birth

Clinical Week 40

Heart- pressure difference closes foramen ovale leaving a fossa ovalis

Glossary of Terms

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UNSW Embryology ISBN: 978 0 7334 2609 4

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