UNSW Embryology

Week 2 references

© Dr Mark Hill (2009)

Acknowledgements

Reading

• Human Embryology (2nd ed.) Larson Ch1 p1-32
• The Developing Human: Clinically Oriented Embryology (6th ed.) Moore and Persaud
• Before we Are Born (5th ed.) Moore and Persaud Ch
• Essentials of Human Embryology Larson Ch1 p1-16
• Human Embryology Fitzgerald and Fitzgerald

References

• Duc-Goiran P, Mignot TM, Bourgeois C, Ferre F Embryo-maternal interactions at the implantation site: a delicate equilibrium. Eur J Obstet Gynecol Reprod Biol 1999 Mar;83(1):85-100
  • Blastocyst implantation and successful establishment of pregnancy require delicate interactions between the embryo and the maternal environment. During preimplantation, maternal/embryo communication is mediated by the trophectoderm. In the late luteal phase, physiological changes occur in the endometrium to allow blastocyst implantation. The "window of implantation" represents the period of maximum uterine receptivity for implantation. In response to signals from the embryo, pregnancy-specific proteins are released in maternal serum and a series of morphological, biochemical and immunological changes occur in the uterine environment. These systemic and local modifications can be considered to constitute "the maternal recognition of pregnancy". The human hemochorial placenta arises primarily through proliferation, migration and invasion of the endometrium and its vasculature by the embryonic trophoblast. The complex invasive processes accompanying implantation of the embryo are controlled at the embryo-maternal interface by factors from decidualized endometrium and the trophoblast itself. An inflammatory reaction and a proper maternal immune response allow survival and development of the feto-placental unit. In this review, we focus on interactions between trophoblast and uterine tissues and on cellular mechanisms and molecular signals involved in the closely regulated process of implantation.

Recent Implantation Reviews

• Rinkenberger JL, et al.  Molecular genetics of implantation in the mouse. Dev Genet. 1997;21(1):6-20. Review.
• Burrows TD, et al.  Trophoblast migration during human placental implantation. Hum Reprod Update. 1996 Jul-Aug;2(4):307-21. Review.
• Schultz GA, et al.  Biology and genetics of implantation. Dev Genet. 1997;21(1):1-5. Review. No abstract available.
• Coutifaris C, et al. Integrins, endometrial maturation, & human embryo implantation. Semin Reprod Endocrinol. 1998;16(3):219-29. Review.
• Rogers PA. Current studies on human implantation: a brief overview. Reprod Fertil Dev. 1995;7(6):1395-9. Review.
• Critchley HO. Factors of importance for implantation and problems after treatment for childhood cancer. Med Pediatr Oncol. 1999 Jul;33(1):9-14. Review.  
• Duc-Goiran P, et al.   Embryo-maternal interactions at the implantation site: a delicate equilibrium. Eur J Obstet Gynecol Reprod Biol. 1999 Mar;83(1):85-100. Review.
• Salamonsen LA.  Role of proteases in implantation. Rev Reprod. 1999 Jan;4(1):11-22. Review.
• Tabibzadeh S.  Molecular control of the implantation window. Hum Reprod Update. 1998 Sep-Oct;4(5):465-71. Review.
• Rice A, et al. Cytokines in implantation. Cytokine Growth Factor Rev. 1998 Sep-Dec;9(3-4):287-96. Review.  
• Carson DD, et al.  Mucin and proteoglycan functions in embryo implantation. Bioessays. 1998 Jul;20(7):577-83. Review.
• Ghosh D, et al. Recent developments in endocrinology and paracrinology of blastocyst implantation in the primate. Hum Reprod Update. 1998 Mar-Apr;4(2):153-68. Review.  
• Fein A, et al.  Peri-implantation mouse embryos: an in vitro assay for assessing serum-associated embryotoxicity in women with reproductive disorders. Reprod Toxicol. 1998 Mar-Apr;12(2):155-9. Review. No abstract available.
• MacCalman CD, et al.  Type 2 cadherins in the human endometrium and placenta: their putative roles in human implantation and placentation. Am J Reprod Immunol. 1998 Feb;39(2):96-107. Review.
• Klentzeris LD.  The role of endometrium in implantation. Hum Reprod. 1997 Nov;12(11 Suppl):170-5. Review.
•  Aplin JD.  Adhesion molecules in implantation. Rev Reprod. 1997 May;2(2):84-93. Review.
• Lockwood CJ, et al.  Decidual cell regulation of hemostasis during implantation and menstruation. Ann N Y Acad Sci. 1997 Sep 26;828:188-93. Review.  
• Tabibzadeh S Implantation: from basics to the clinic. Ann N Y Acad Sci. 1997 Sep 26;828:131-6. Review. No abstract available.
• Sueoka K, et al.  Integrins and reproductive physiology: expression and modulation in fertilization, embryogenesis, and implantation. Fertil Steril. 1997 May;67(5):799-811. Review.
• Nie GY, et al.  Hormonal and non-hormonal agents at implantation as targets for contraception. Reprod Fertil Dev. 1997;9(1):65-76. Review.  
• Barkai U, et al.  Intrauterine signaling and embryonic implantation. Biol Signals. 1996 Mar-Apr;5(2):111-21. Review.
• Grummer R, et al. Expression pattern of different gap junction connexins is related to embryo implantation. Int J Dev Biol. 1996 Feb;40(1):361-7. Review.
• Loke YW, et al.  Immunology of human implantation: an evolutionary perspective. Hum Reprod. 1996 Feb;11(2):283-6. Review.

Recent Reviews Gastrulation

• Tam PP, et al. Mouse gastrulation: the formation of a mammalian body plan. Mech Dev. 1997 Nov;68(1-2):3-25. Review.
  • a key Australian researcher at the Childrens Medical Research Institute, Westmead
• Lemaire L, et al. Gastrulation and homeobox genes in chick embryos. Mech Dev. 1997 Sep;67(1):3-16. Review.
• Arendt D, et al. Dorsal or ventral: similarities in fate maps and gastrulation patterns in annelids, arthropods and chordates. Mech Dev. 1997 Jan;61(1-2):7-21. Review.
• Camus A, et al. The organizer of the gastrulating mouse embryo. Curr Top Dev Biol. 1999;45:117-53. Review.
• Boncinelli E, et al. Homeobox genes in vertebrate gastrulation. Curr Opin Genet Dev. 1995 Oct;5(5):619-27. Review.
• Wolpert L. Gastrulation and the evolution of development. Dev Suppl. 1992;:7-13.
• McClay DR. Gastrulation. Curr Opin Genet Dev. 1991 Aug;1(2):191-5. Review.

Recent Articles Gastrulation

• Tam PP, et al.The allocation of epiblast cells to the embryonic heart and other mesodermal lineages: the role of ingression and tissue movement during gastrulation. Development. 1997 May;124(9):1631-42.
• Wood HB, et al. Comparative expression of the mouse Sox1, Sox2 and Sox3 genes from pre-gastrulation to early somite stages. Mech Dev. 1999 Aug 1;86(1-2):197-201
• Winklbauer R, et al. Vegetal rotation, a new gastrulation movement involved in the internalization of the mesoderm and endoderm in Xenopus. Development. 1999;126(16):3703-3713.
• Gu Z, et al. The type I serine/threonine kinase receptor ActRIA (ALK2) is required for gastrulation of the mouse embryo. Development. 1999 Jun;126(11):2551-61.
• Saxton TM, et al. Morphogenetic movements at gastrulation require the SH2 tyrosine phosphatase Shp2. Proc Natl Acad Sci U S A. 1999 Mar 30;96(7):3790-5.
• Sugihara K, et al. Rac1 is required for the formation of three germ layers during gastrulation. Oncogene. 1998 Dec 31;17(26):3427-33.
• Zwijsen A, et al. Ectopic expression of the transforming growth factor beta type II receptor disrupts mesoderm organisation during mouse gastrulation. Dev Dyn. 1999 Feb;214(2):141-51.
• Varlet I, et al. nodal expression in the primitive endoderm is required for specification of the anterior axis during mouse gastrulation. Development. 1997 Mar;124(5):1033-44.
• Sanders EJ, et al. Patterns of cell death during gastrulation in chick and mouse embryos. Anat Embryol (Berl). 1997 Feb;195(2):147-54.
• Winklbauer R, et al. Fibronectin, mesoderm migration, and gastrulation in Xenopus. Dev Biol. 1996 Aug 1;177(2):413-26.
• Bellomo D, et al. Cell proliferation in mammalian gastrulation: the ventral node and notochord are relatively quiescent. Dev Dyn. 1996 Apr;205(4):471-85.
• Malinda KM, et al. Four-dimensional microscopic analysis of the filopodial behavior of primary mesenchyme cells during gastrulation in the sea urchin embryo. Dev Biol. 1995 Dec;172(2):552-66.
• Sulik KK. Critical periods for alcohol teratogenesis in mice, with special reference to the gastrulation stage of embryogenesis. Ciba Found Symp. 1984;105:124-41.

Recent Articles Notochord

• Prince VE, et al. Hox gene expression reveals regionalization along the anteroposterior axis of the zebrafish notochord. Dev Genes Evol. 1998 Nov;208(9):517-22.
• Teillet MA, et al. The relationships between notochord and floor plate in vertebrate development revisited. Proc Natl Acad Sci U S A. 1998 Sep 29;95(20):11733-8.

Note that reference lists are only relevant to the date of the original search.

Quick Links

Week 2 Pages:

Introduction | Timeline Week 2 | Carnegie stages 5 to 7 | Abnormalities | Blastocyst Implantation | Sites of Implantation | Bilaminar Embryo | Embryonic Cavitites | Early Placentation | Molecular | Stem Cells | References | Text only | WWW Links | Movies - Week 2

Development Notes ----------------- Menstrual Cycle Week 1 Week 2 Week 3 Week 4 Placenta Serial Images Genes/DNA Molecular Dev Abnormal Dev Postnatal Dev Notes Index

System Notes ----------------- Heart/Cardiovascular Respiratory Coelomic cavity Gastrointestinal Tract Head and Neck Neural Neural Crest Eye Ear Nose Endocrine Urogenital Musculoskeletal Integumentary

Movies ----------------- Embryo Growth Ultrasound Week 1 Week 2 Week 3 Week 4 Stage 13/14 Stage 22 Neural Head and Neck Heart Vasculature Gastrointestinal Urogenital Other Embryos Larsen Internet

Other Embryos ----------------- Chicken Fly Frog Mouse Rabbit Rat Worm Zebrafish Guinea Pig

UNSW Embryology ISBN: 978 0 7334 2609 4

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