UNSW Embryology

Development of the Kidney and Reproduction Systems

© Dr Mark Hill (2004)

Acknowledgements

Introduction

This section of notes covers both kidney and genital development. The kidneys filter and excrete waste body fliuds. The gonads are involved in developing secondary sex characteristics and generation of sex cells (gametes) for reproduction. These 2 systems have entirely different mature functions but are closely associated by the anatomical requirements of the mature system. The mesonephric/paramesonephric duct changes are one of the first male/female differences that occur in development, while external genitaila remain indeterminate in appearance for quite a while.

The kidneys, urinary tract and the majority of the reproductive organs, arise in the intermediate mesoderm between the somites and the lateral plate. The kidney goes through 3 stages of development that recapitulate evolution of the kidney; pronephros, mesonephros, metanephros.

The specialized structures within the kidney involved with filtering the blood, reabsorbtion, secretion, and generation of urine are called nephrons. (More? see about Nephrons)

Some Recent Findings

Reading

  • UNSW Embryology Selected XXXX References
  • Objectives

    Learning activities

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    Kidney Lectures: ANAT2300 Vertebrate Development- Kidney

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    Following links to Internet Movies large files Urogenital animations page

    Video

    Development Overview

    Stage 13/14 Pig Overview

    These serial sections are from the top of the lefthand primitive kidney through to the curve at the base of the kidney. Towards the bottom of each frame is the midline of the embryo.The full size images show much more detail. This panel is also available as a large image on the Pig st13/14 page.

    The main feature to observe is the appearance medially of the mature metanephric region with the forming glomeruli, laterally the mesonephros still forms the bulk of the kidney (and the lateral dorsal bulge seen in the embryo) with the mesonephric duct and subcardinal vein the prominant channels within the kidney. The large vessel at the bottom left of each image is the dorsal aorta.

    Beside the new glomeruli appearing as a slight thickening of the medial wall of the kidney is the genital ridge. This region will contribute to the gonad.

    More Detail? Developmental Overview

    pig small renal

    Development Terms

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