Information relating to chemical safety is continuously changing and the most current source of Material Safety Data Sheet (MSDS) should be used for accurate information.
The information used in these current MSDS's is modified from 1999 generic sources. In all cases there may be specific modifications or additional entries for chemicals not listed.
This information is provided for educational purposes only.
Page Links: Introduction | About Lead | MSDS for Lead | Physical Data | Health Hazard Data | Vermont SIRI MSDS Collection | Chemical Terms |
The information below is for Lead at the concentration of 1000 PPM (0.100% Weight/Volume).
Lead is a naturally occuring heavy metal.
Historically, lead was added (due to its physical properties) at the industrial level to various substances found in our environment including: paint, petrol, cabling, pipes, bullets, shielding and also mixed with other metals. Similarly, it can be found as a long-term contaminant of industrial sites or historic buildings soil, water or water sediments.
Currently, due to a better knowledge of its health effects, it has been either removed or replaced in many products.
1 - PRODUCT IDENTIFICATION
PRODUCT NAME: LEAD, 1000 PPM (0.100% W/V)
FORMULA: PB3O4 IN HNO3
FORMULA WT: 207.20
CAS NO.: - -
PRODUCT CODES: 6930
EFFECTIVE: 11/20/85
REVISION #01
PRECAUTIONARY LABELLING
BAKER SAF-T-DATA(TM) SYSTEM
HEALTH - 2 MODERATE
FLAMMABILITY - 0 NONE
REACTIVITY - 1 SLIGHT
CONTACT - 3 SEVERE (CORROSIVE)
HAZARD RATINGS ARE 0 TO 4 (0 = NO HAZARD; 4 = EXTREME HAZARD).
LABORATORY PROTECTIVE EQUIPMENT
GOGGLES & SHIELD; LAB COAT & APRON; VENT HOOD; PROPER GLOVES
PRECAUTIONARY LABEL STATEMENTS
DANGER
CAUSES BURNS
HARMFUL IF SWALLOWED
DO NOT GET IN EYES, ON SKIN, ON CLOTHING.
AVOID BREATHING VAPOR. KEEP IN TIGHTLY CLOSED CONTAINER. USE WITH ADEQUATE
VENTILATION. WASH THOROUGHLY AFTER HANDLING.
SAF-T-DATA(TM) STORAGE COLOR CODE: WHITE (CORROSIVE)
------------------------------------------------------------------------------
2 - HAZARDOUS COMPONENTS
------------------------------------------------------------------------------
COMPONENT % CAS NO.
LEAD OXIDE 0-1 1314-41-6
NITRIC ACID 1-2 7697-37-2
3 - PHYSICAL DATA
BOILING POINT: 100 C ( 212 F) VAPOR PRESSURE(MM HG): N/A
MELTING POINT: 0 C ( 32 F) VAPOR DENSITY(AIR=1): N/A
SPECIFIC GRAVITY: 1.00 EVAPORATION RATE: N/A
(H2O=1) (BUTYL ACETATE=1)
MSDS for LEAD, 1000 PPM (0.100% W/V) Page 2
SOLUBILITY(H2O): COMPLETE (IN ALL PROPORTIONS) % VOLATILES BY VOLUME: N/A
APPEARANCE & ODOR: CLEAR, COLORLESS SOLUTION.
4 - FIRE AND EXPLOSION HAZARD DATA
FLASH POINT (CLOSED CUP N/A NFPA 704M RATING: 3-0-0
FLAMMABLE LIMITS: UPPER - N/A % LOWER - N/A %
FIRE EXTINGUISHING MEDIA
USE EXTINGUISHING MEDIA APPROPRIATE FOR SURROUNDING FIRE.
SPECIAL FIRE-FIGHTING PROCEDURES
FIREFIGHTERS SHOULD WEAR PROPER PROTECTIVE EQUIPMENT AND SELF-CONTAINED
BREATHING APPARATUS WITH FULL FACEPIECE OPERATED IN POSITIVE PRESSURE MODE.
TOXIC GASES PRODUCED
NITROGEN OXIDES
5 - HEALTH HAZARD DATA
THRESHOLD LIMIT VALUE (TLV/TWA): 0.15 MG/M3 ( PPM)
TOXICITY: LD50 (IPR-RAT)(MG/KG) - 630
CARCINOGENICITY: NTP: NO IARC: NO Z LIST: NO OSHA REG: NO
EFFECTS OF OVEREXPOSURE
LIQUID MAY CAUSE BURNS TO SKIN AND EYES.
VAPORS MAY BE IRRITATING TO EYES, NOSE AND THROAT.
INHALATION OF VAPORS MAY CAUSE COUGHING AND DIFFICULT BREATHING.
CHRONIC EFFECTS RESULTING FROM LOW LEVEL EXPOSURE TO LEAD COMPOUNDS
MAY INCLUDE ANEMIA, KIDNEY DAMAGE, IMPAIRED EYESIGHT, AND LEAD
BUILD-UP IN THE CENTRAL NERVOUS SYSTEM (PARTICULARLY THE BRAIN).
TARGET ORGANS
NONE IDENTIFIED
MEDICAL CONDITIONS GENERALLY AGGRAVATED BY EXPOSURE
NONE IDENTIFIED
ROUTES OF ENTRY
NONE INDICATED
EMERGENCY AND FIRST AID PROCEDURES
CALL A PHYSICIAN.
IF SWALLOWED, DO NOT INDUCE VOMITING; IF CONSCIOUS, GIVE WATER, MILK, OR
MILK OF MAGNESIA.
IN CASE OF CONTACT, IMMEDIATELY FLUSH EYES OR SKIN WITH PLENTY OF WATER FOR
AT LEAST 15 MINUTES WHILE REMOVING CONTAMINATED CLOTHING AND SHOES.
WASH CLOTHING BEFORE RE-USE.
TOXICITY TEST RESULTS AND SAFETY AND HEALTH EFFECTS ARE BASED ON
THE SOLUTE.
6 - REACTIVITY DATA
STABILITY: STABLE HAZARDOUS POLYMERIZATION: WILL NOT OCCUR
CONDITIONS TO AVOID: NONE DOCUMENTED
INCOMPATIBLES: STRONG REDUCING AGENTS
DECOMPOSITION PRODUCTS: OXIDES OF NITROGEN
7 - SPILL AND DISPOSAL PROCEDURES
STEPS TO BE TAKEN IN THE EVENT OF A SPILL OR DISCHARGE
WEAR SELF-CONTAINED BREATHING APPARATUS AND FULL PROTECTIVE CLOTHING.
STOP LEAK IF YOU CAN DO SO WITHOUT RISK. USE WATER SPRAY TO REDUCE VAPORS.
TAKE UP WITH SAND OR OTHER NON-COMBUSTIBLE ABSORBENT MATERIAL AND PLACE
INTO CONTAINER FOR LATER DISPOSAL. FLUSH SPILL AREA WITH WATER.
DISPOSAL PROCEDURE
DISPOSE IN ACCORDANCE WITH ALL APPLICABLE FEDERAL, STATE, AND LOCAL
ENVIRONMENTAL REGULATIONS.
EPA HAZARDOUS WASTE NUMBER: D002 (CORROSIVE WASTE)
8 - PROTECTIVE EQUIPMENT
EYE/SKIN PROTECTION: THIS IS A LABORATORY-USE PRODUCT FOR WHICH NO
INDUSTRIAL PROTECTIVE EQUIPMENT HAS BEEN
DESIGNATED.
9 - STORAGE AND HANDLING PRECAUTIONS
SAF-T-DATA(TM) STORAGE COLOR CODE: WHITE (CORROSIVE)
SPECIAL PRECAUTIONS
KEEP CONTAINER TIGHTLY CLOSED. STORE IN CORROSION-PROOF AREA.
10 - TRANSPORTATION DATA AND ADDITIONAL INFORMATION
MSDS for LEAD, 1000 PPM (0.100% W/V) Page 4
DOMESTIC (D.O.T.)
PROPER SHIPPING NAME NITRIC ACID, 40% OR LESS SOLUTION
HAZARD CLASS CORROSIVE MATERIAL (LIQUID)
UN/NA NA1760
LABELS CORROSIVE
REPORTABLE QUANTITY 1000 LBS.
INTERNATIONAL (I.M.O.)
PROPER SHIPPING NAME NITRIC ACID, SOLUTION
HAZARD CLASS 8
UN/NA UN2031
LABELS CORROSIVE
Some Chemical Terms (relating to harmful effects)
A carcinogen is a chemical known or believed to cause cancer in humans. The number of known carcinogens is comparatively small, but many more chemicals are suspected to be carcinogenic.
ED50: Effective dose - the amount of material required to produce a specified effect in 50% of an animal population. (See qualification in the definition of LD50).
LD50: is the dose of a chemical which kills 50% of a sample population. In full reporting, the dose, treatment and observation period should be given. Further, LD50 and ED50 values are strictly only comparable when the age, sex and nutritional state of the animals is specified. Nevertheless, LD50 values are widely reported as a measure of the potential toxicity of chemicals.
A mutagen is an agent that changes the hereditary genetic material which is a part of every living cell. Such a mutation is probably an early step in the sequence of events that ultimately leads to the development of cancer.
TLV (Threshold Limit Value) is the maximum permissible concentration of a material, generally expressed in parts per million in air for some defined period of time (often 8 hours). These values, which may differ from country to country, are often backed up by regulation and are therefore often legally enforceable.
Look at types of Abnormal Development that can occur during development.
Alternatively, look at normal development. Development Notes
For those wanting to see dynamic processes of development (and have a reasonably quick connection) then the Movies pages are good for watching changes occur.
The study of human development has relied extensively on studying the process in other model animals. For those wanting to see the process of development in other species then the other embryos pages are a good start.
Home Page
Embryo stages
Fetus
Dev Notes 1
Dev Notes 2
System Notes
Acknowledgements
Abnormal
Major System Abnormalities
Maternal Factors
MSDS Index
MSDS - Lead
Fetal Origins Hypothesis
Movies
Audio
Class Notes
Serial Images
K12 Students
Abnormal
Embryology in the News
Histology
Site Map
School of Med Sci
UNSW Medicine
University of NSW
UNSW Cell Biology
NCBI Books
Dev Biol (Gilbert)
Abnormalities in human development can be due to many different maternal factors, this page gives background information on the topic of lead.
Furthermore the Fetal Origins Hypothesis now suggests that uterine developmental effects, as sometimes indicated by low birth weight, can also have an impact on future health outcomes.
This chemical information is provided for educational use only and specific chemical data should be saught from manufacturers or suppliers of chemicals.
See also the Prenatal Diagnosis page NSW Pamphlet Checking your baby's health before birth.
Please email Dr Mark Hill if you wish to make a comment about this current project.