Philadelphia chromosome

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Introduction

The Philadelphia chromosome or Philadelphia translocation refers to a chromosomal abnormality resulting from a reciprocal translocation between chromosome 9 and 22. This is described by the genetic molecular shorthand t(9;22)(q34;q11)).

The translocation is associated with the disease chronic myelogenous leukemia (CML).


(More? Abnormal Development - Genetic | Cell Division - Meiosis | Cell Division - Mitosis | Week 1 | PMID17671636)