File:Zebrafish Wdr18 expression 01.jpg

Zebrafish Wdr18 Expression

• A - wdr18 is maternally expressed.
• B - Expression pattern of wdr18 at the 75%-epiboly stage. Black arrow indicates the staining of dorsal forerunner cells (DFCs).
• C - wdr18 expression is detected around the Kupffer's vesicle (white arrowhead) at the 6-somite stage. Inset is an overexposed magnified image showing elevated wdr18 expression around the KV. (See also detailed image)
• D - wdr18 is detected ubiquitously throughout the whole embryo at 18-somite stage.
• E - At 3 dpf, wdr18 is expressed in endodermal organs, including the exocrine pancreas (black arrow), liver (white arrow), and intestine.

Wdr18 - is a member of the WD-repeat protein family found in all eukaryotes. The WD repeat consists of a 44 to 60 amino acid residue sequence that typically contains a GH dipeptide located 11 to 24 residues from its N-terminus and ends with a WD dipeptide at its C-terminus. Wdr18 is maternally expressed from the 1–4 cell stage.

Links: Image - full figure | Image - Panel C | Zebrafish Development

Reference

<pubmed>21876750</pubmed>| PLoS One.

Copyright

© 2011 Gao et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Figure 1. journal.pone.0023386.g001.jpg doi:10.1371/journal.pone.0023386.g001 original figure altered in size and labeling.