File:Trisomy 21 newborn.jpg

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Trisomy 21 (Down Syndrome) Newborn

Down syndrome or trisomy 21 is caused by nondisjunction of chromosome 21 in a parent who is chromosomally normal and is one of the most common chromosomal abnormalities in liveborn children.

The frequency of trisomy 21 in the population is approximately 1 in 650 to 1,000 live births, in Australia between 1991-97 there were 2,358 Trisomy 21 (Down) infants.

  • The normal human karyotypes contain 22 pairs of autosomal chromosomes and one pair of sex chromosomes.
  • The karyotype is the characteristic chromosome complement as identified by staining and can only be identified during cell division when chromosomes are folded.
  • The chromosomes when organised as an image in sequence are called a karyogram or idiogram.


Links: Trisomy 21


Image Source: CDC Dr. Godfrey P. Oakley


UNSW Embryology http://embryology.med.unsw.edu.au/Defect/page21.htm

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current14:37, 5 August 2009Thumbnail for version as of 14:37, 5 August 2009320 × 240 (16 KB)S8600021 (talk | contribs)Trisomy 21 (Down Syndrome) Newborn Down syndrome or trisomy 21 is caused by nondisjunction of chromosome 21 in a parent who is chromosomally normal and is one of the most common chromosomal abnormalities in liveborn children. The frequency of trisom

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