File:Signalling factors in lung branching cartoon.png
Original file (1,201 × 657 pixels, file size: 219 KB, MIME type: image/png)
Signalling factors in lung branching cartoon
A graphical summary of the modelled interactions of the signaling factors in lung bud during morphogenesis.
GF10 is transcribed at high levels in the distal mesenchyme (grey) and experiments suggest that FGF10 promotes both the proliferation of the endoderm and its outward movement (green arrow). FGF10 stimulates the expression of SHH in the epithelium (red). SHH reversibly binds its receptor Ptc1 which is expressed in the mesenchyme (grey). SHH-Ptc binding results in the repression of FGF10 expression.
Reference
Menshykau D, Kraemer C, Iber D (2012) Branch Mode Selection during Early Lung Development. PLoS Comput Biol 8(2): e1002377. doi:10.1371/journal.pcbi.1002377
http://www.ploscompbiol.org/article/info%3Adoi%2F10.1371%2Fjournal.pcbi.1002377
Copyright Information
© 2012 Menshykau et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
--Mark Hill (talk) 14:50 7 November 2014 (EST) Assessment - Figure relates to project topic contains reference, copyright and student template. reference should have been formatted with pubmed extension. There is no further description to identify when this signalling process occurs (embryonic/fetal). There should also be an explanation of the factors in the figure.
- Note - This image was originally uploaded as part of an undergraduate science student project and may contain inaccuracies in either description or acknowledgements. Students have been advised in writing concerning the reuse of content and may accidentally have misunderstood the original terms of use. If image reuse on this non-commercial educational site infringes your existing copyright, please contact the site editor for immediate removal.
File history
Click on a date/time to view the file as it appeared at that time.
Date/Time | Thumbnail | Dimensions | User | Comment | |
---|---|---|---|---|---|
current | 01:30, 24 October 2014 | 1,201 × 657 (219 KB) | Z3332339 (talk | contribs) | ==Signalling factors in lung branching cartoon== A graphical summary of the modelled interactions of the signaling factors in lung bud during morphogenesis. FGF10 is transcribed at high levels in the distal mesenchyme (grey) and experiments suggest... |
You cannot overwrite this file.
File usage
The following 2 pages use this file: