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Chromosome Connections in Meiosis

Kinetochores attach homologous chromosomes to opposite halves of the spindle.

Homologs are held together by chiasmata, in which recombinant chromatids cross each other.

Sisters are held together by cohesins and possibly by catenation of centromeric DNA threads, which have been observed in human mitosis.

Cohesion is released in two steps:

on chromosome arms to resolve chiasmata and separate homologs in the first meiotic division.
around centromeres to separate sisters in the second meiotic division.

Reference

<pubmed>20231873</pubmed>| PLoS Biol.

Copyright

© 2010 Talbert, Henikoff. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Figure 1. Journal.pbio.1000326.g001.png

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	Date/Time	Thumbnail	Dimensions	User	Comment
current	18:27, 27 July 2010		600 × 397 (35 KB)	S8600021 (talk \| contribs)	Chromosome connections in meiosis. Kinetochores attach homologous chromosomes to opposite halves of the spindle. Homologs are held together by chiasmata, in which recombinant chromatids cross each other. Sisters are held together by cohesins and poss

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@@ Line 11: / Line 11: @@
 # around centromeres to separate sisters in the second meiotic division.
-Figure 1. Journal.pbio.1000326.g001.png
 ===Reference===
@@ Line 19: / Line 16: @@
 <pubmed>20231873</pubmed>| [http://www.plosbiology.org/article/info%3Adoi%2F10.1371%2Fjournal.pbio.1000326 PLoS Biol.]
-Citation: Talbert PB, Henikoff S (2010) Centromeres Convert but Don't Cross. PLoS Biol 8(3): e1000326. doi:10.1371/journal.pbio.1000326
-Published: March 9, 2010
+====Copyright====
-Copyright: © 2010 Talbert, Henikoff. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
+© 2010 Talbert, Henikoff. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
+Figure 1. Journal.pbio.1000326.g001.png
 [[Category:Meiosis]] [[Category:Cartoon]]