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- 23:51, 2 August 2010 S8600021 talk contribs uploaded File:Craniofrontonasal syndrome.jpg (==Craniofrontonasal syndrome== Craniofrontonasal syndrome (CFNS) is a human X-linked developmental disorder caused by a mutation in ephrin-B1 affecting mainly females. Characterised by abnormal development of cranial and nasal bones, craniosynostosis (pr)