Nutrition

From Embryology
Notice - Mark Hill
Currently this page is only a template and will be updated (this notice removed when completed).

Introduction

This current page is a start page for your exploration of topics related to nutrition and development.

While there are many sites and information available concerning postnatal nutrition, prenatally research has mainly focussed on developmental effects of specific deficiencies (folate and iodine) and the teratogenic effects of retinoic acid.

See also the National Health and Medical Research Council (NHMRC) publication NHMRC - Nutrient Reference Values for Australia and New Zealand Including Recommended Dietary Intakes.[1] "The Nutrient Reference Values outline the levels of intake of essential nutrients considered to be adequate to meet the known nutritional needs of practically all healthy people for prevention of deficiency states. The document can be used by health professionals to assess the likelihood of inadequate intake in individuals or groups of people."

Folic Acid

In the U.S.A. the Food and Drug Administration in 1996 authorized that all enriched cereal grain products be fortified with folic acid, with optional fortification beginning in March 1996 and mandatory fortification in January 1998.

In 2001, the Australian estimated birth prevalence of neural tube defects was 0.5 per 1,000 births (National Perinatal Statistics Unit). Low maternal dietary folic acid (folate) has been shown to be associated with the development of neural tube defects.

Links: Folic Acid and Neural Tube Defects

Iodine

"Iodine is an essential nutrient that humans need in very small quantities. The thyroid uses iodine to produce hormones vital to ensure normal development of the brain and nervous system before birth, in babies and young children. For this reason, it is very important that pregnant and breastfeeding women get enough iodine.

The National Health and Medical Research Council recommends that all women who are pregnant, breastfeeding or considering pregnancy, take an iodine supplement of 150 micrograms (μg) each day. Women with pre-existing thyroid conditions should seek advice from their medical practitioner prior to taking a supplement."

(text from Iodine supplementation for Pregnant and Breastfeeding Women 2010 )

Links: Iodine Deficiency | Iodine supplementation for Pregnant and Breastfeeding Women NHMRC - Nutrition & Diet Publications

Vitamins

vitamin A

Retinoic acid is a metabolite of vitamin A (retinol).


Links: Developmental Signals - Retinoic acid

vitamin B

Eight separate water-soluble vitamins that play important roles in cell metabolism. Folic acid or vitamin B9 (folacin) and folate (naturally occurring form) are an important dietary requirement for normal neural development. Low levels have been show associated with neural tube defects including spina bifida.

Links: Neural System Development | Neural System - Abnormalities

vitamin C

| entry to be edited |

vitamin D

Vitamin D is important Circulating 25-hydroxyvitamin D3 (25[OH]D), the most commonly used index of vitamin D status, is converted to the active hormone 1,25 dihydroxyvitamin D3 (1,25[OH]2D), which, operating through the vitamin D receptor (VDR).

The vitamin D receptor belongs to the nuclear receptor superfamily.

USA Institute of Medicine expert committee "calcium requirements varied with age, from 700 mg a day for children aged 1-3 years up to 1200 mg a day for women aged 51 to 70 and 1300 mg a day for teenagers and pregnant and lactating women."

  • UK - Avoidance of vitamin D deficiency in pregnancy in the United Kingdom: the case for a unified approach in National policy.[2]
  • USA 2004 - Vitamin D requirements during pregnancy.[3]
Links: Dietary Reference Intakes for Calcium and Vitamin D | Paediatric Endocrine Group; Paediatric Bone Australasia. Prevention and treatment of infant and childhood vitamin D deficiency in Australia and New Zealand: a consensus statement. 2006 PMID16948623 | Vitamin D - a review 2008 PMID19142273 | AFP)

vitamin E

| entry to be edited |

vitamin K

A generic term for derivatives of 2-methyl-1,4-naphthoquinone that have coagulation activity. Daily requirement for vitamin K is about 1 µg/kg. In newborns vitamin K nutrition is at risk.

References

  1. Nutrient Reference Values for Australia and New Zealand Including Recommended Dietary Intakes. (2006) http://www.nhmrc.gov.au/publications/synopses/n35syn.htm PDF
  2. <pubmed>20594390</pubmed>
  3. <pubmed>15585798</pubmed>

Reviews

<pubmed>21291560</pubmed>

Articles

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Terms

  • Adequate Intake - (AI) The average daily nutrient intake level based on observed or experimentally-determined approximations or estimates of nutrient intake by a group (or groups) of apparently healthy people that are assumed to be adequate. Used when an RDI cannot be determined.
  • Estimated Average Requirement - (EAR) A daily nutrient level estimated to meet the requirements of half the healthy individuals in a particular life stage and gender group.
  • Recommended Dietary Intake - (RDI) The average daily dietary intake level that is sufficient to meet the nutrient requirements of nearly all (97–98 per cent) healthy individuals in a particular life stage and gender group.
  • Upper Level of Intake - (UL) The highest average daily nutrient intake level likely to pose no adverse health effects to almost all individuals in the general population. As intake increases above the UL, the potential risk of adverse effects increases.


Some terms from NHMRC publication, adapted from Food and Nutrition Board: Institute of Medicine (USA and Canada).

External Links

External Links Notice - The dynamic nature of the internet may mean that some of these listed links may no longer function. If the link no longer works search the web with the link text or name. Links to any external commercial sites are provided for information purposes only and should never be considered an endorsement. UNSW Embryology is provided as an educational resource with no clinical information or commercial affiliation.

Glossary Links

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Cite this page: Hill, M.A. (2024, June 3) Embryology Nutrition. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Nutrition

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© Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G