File:Integumentary touch dome functions.jpg
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Merkel cells and touch domes: more than mechanosensory functions? Exp Dermatol. 2014 Oct;23(10):692-5. doi: 10.1111/exd.12456. Epub 2014 Jul 16.
Integumentary touch dome functions
Xiao Y1, Williams JS, Brownell I.
Abstract
The touch dome (TD) is an innervated structure in the epidermis of mammalian skin. Composed of specialized keratinocytes and neuroendocrine Merkel cells, the TD has distinct molecular characteristics compared to the surrounding epidermal keratinocytes. Much of the research on Merkel cell function has focused on their role in mechanosensation, specifically light touch. Recently, more has been discovered about Merkel cell molecular characteristics and their cells of origin. Here we review Merkel cell and TD biology, and discuss potential functions beyond mechanosensation.
Published 2014. This article is a U.S. Government work and is in the public domain in the USA.
KEYWORDS: Merkel cell; endocrine; immune; mechanosensation; touch dome
PMID 24862916 PMCID: PMC4180785 DOI: 10.1111/exd.12456
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 10:02, 22 September 2016 | | 893 × 556 (97 KB) | Z8600021 (talk | contribs) | |
| 10:02, 22 September 2016 |  | 950 × 664 (115 KB) | Z8600021 (talk | contribs) | Merkel cells and touch domes: more than mechanosensory functions? Exp Dermatol. 2014 Oct;23(10):692-5. doi: 10.1111/exd.12456. Epub 2014 Jul 16. ==Integumentary touch dome functions== Xiao Y1, Williams JS, Brownell I. Abstract The touch dome (TD) i... |
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