File:Hair follicle development.jpg

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Revision as of 00:37, 22 April 2010 by S8600021 (talk | contribs) (Organization of the epidermis. Hair follicles contain stem cells located in the bulge (b, green), with the potential to generate lower hair follicle (lf), sebaceous gland (sg, orange) upper follicle (uf) and interfollicular epidermis (IFE, beige). The s)
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Organization of the epidermis.

Hair follicles contain stem cells located in the bulge (b, green), with the potential to generate lower hair follicle (lf), sebaceous gland (sg, orange) upper follicle (uf) and interfollicular epidermis (IFE, beige). The schematic shows the organization of keratinocytes in the IFE, as proposed by the stem/TA cell hypothesis. The basal layer comprises stem cells (S, blue), transit amplifying cells (TA, dark green), and post-mitotic basal cells (red), which migrate out of the basal layer as they differentiate (arrows).

Original file name: Nature05574-f1.2.jpg

A single type of progenitor cell maintains normal epidermis. Clayton E, Doupe DP, Klein AM, Winton DJ, Simons BD, Jones PH. Nature. 2007 Mar 8;446(7132):185-9. PMID: 17330052

MRC - Phil Jones Laboratory


Reprinted by permission from Macmillan Publishers Ltd: Nature. 2007 Mar 8;446(7132):185-9, copyright (2007)

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current00:37, 22 April 2010Thumbnail for version as of 00:37, 22 April 2010800 × 663 (191 KB)S8600021 (talk | contribs)Organization of the epidermis. Hair follicles contain stem cells located in the bulge (b, green), with the potential to generate lower hair follicle (lf), sebaceous gland (sg, orange) upper follicle (uf) and interfollicular epidermis (IFE, beige). The s