Developmental Mechanism - Cell Junctions: Difference between revisions
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==Gap Junction== | |||
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* Discovered by J.P. Revel & M.J. Karnovsky in 1967 | |||
* allowing direct communication between cells (open & close) | |||
* close membranes 2 - 3 nm apart | |||
* connexins form hollow 1.5 nm diameter cylinders | |||
* heart muscle, smooth muscle electrical and chemical integration as a single functional unit | |||
* Also in embryonic development (see {{Blastocyst}}) | |||
| [[File:Gap_junction_01.jpg|300px]] | |||
Gap Junction | |||
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Search PubMed: [http://www.ncbi.nlm.nih.gov/pubmed/?term=gap+junction gap junction] | |||
Revision as of 09:07, 26 April 2020
Embryology - 14 Jun 2024 Expand to Translate |
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Introduction
Many developmental mechanisms require dynamic changes in cell adhesion that acts through different types of cell junctions.
Adhesion Cartoons
Adhesion EM Images
- Adhesion EM Images: GIT epithelia EM1 | GIT epithelia EM2 | GIT epithelia EM3 | Desmosome EM
- Adhesion Cartoons: Tight junction | Adherens Junction | Desmosome | Gap Junction
Tight Junction
Tight junction |
Adherens Junction
Cadherin isoform naming was based upon the site of original identification: P-cadherin (placenta cadherin, cadherin 3), E-cadherin (epithelial cadherin cadherin 1), N-cadherin (neural cadherin, cadherin 2). |
Adherens Junction |
Desmosome
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Desmosome |
Gap Junction
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Gap Junction |
Search PubMed: gap junction
References
Reviews
Articles
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Cite this page: Hill, M.A. (2024, June 14) Embryology Developmental Mechanism - Cell Junctions. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Developmental_Mechanism_-_Cell_Junctions
- © Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G