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Exp Dermatol. 2014 Oct;23(10):692-5. doi: 10.1111/exd.12456. Epub 2014 Jul 16.
Exp Dermatol. 2014 Oct;23(10):692-5. doi: 10.1111/exd.12456. Epub 2014 Jul 16.


==Integumentary touch dome functions==


Xiao Y1, Williams JS, Brownell I.
===Reference===


Abstract
<pubmed>24862916</pubmed>


The touch dome (TD) is an innervated structure in the epidermis of mammalian skin. Composed of specialized keratinocytes and neuroendocrine Merkel cells, the TD has distinct molecular characteristics compared to the surrounding epidermal keratinocytes. Much of the research on Merkel cell function has focused on their role in mechanosensation, specifically light touch. Recently, more has been discovered about Merkel cell molecular characteristics and their cells of origin. Here we review Merkel cell and TD biology, and discuss potential functions beyond mechanosensation.
PMID 24862916 PMCID: PMC4180785 DOI: 10.1111/exd.12456
====Copyright====


Published 2014. This article is a U.S. Government work and is in the public domain in the USA.
Published 2014. This article is a U.S. Government work and is in the public domain in the USA.


KEYWORDS: Merkel cell; endocrine; immune; mechanosensation; touch dome
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PMID 24862916 PMCID: PMC4180785 DOI: 10.1111/exd.12456

Revision as of 10:03, 22 September 2016

Merkel cells and touch domes: more than mechanosensory functions? Exp Dermatol. 2014 Oct;23(10):692-5. doi: 10.1111/exd.12456. Epub 2014 Jul 16.


Reference

<pubmed>24862916</pubmed>

PMID 24862916 PMCID: PMC4180785 DOI: 10.1111/exd.12456

Copyright

Published 2014. This article is a U.S. Government work and is in the public domain in the USA.


Cite this page: Hill, M.A. (2024, June 2) Embryology Integumentary touch dome functions.jpg. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/File:Integumentary_touch_dome_functions.jpg

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© Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G

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current10:02, 22 September 2016Thumbnail for version as of 10:02, 22 September 2016893 × 556 (97 KB)Z8600021 (talk | contribs)
10:02, 22 September 2016Thumbnail for version as of 10:02, 22 September 2016950 × 664 (115 KB)Z8600021 (talk | contribs)Merkel cells and touch domes: more than mechanosensory functions? Exp Dermatol. 2014 Oct;23(10):692-5. doi: 10.1111/exd.12456. Epub 2014 Jul 16. ==Integumentary touch dome functions== Xiao Y1, Williams JS, Brownell I. Abstract The touch dome (TD) i...

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