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Diagramatic representation of the steroidogenic pathways in human pre-luteinized follicles (A) and post luteinized follicles (B), demonstrating granulosa dependence on theca cell testosterone steroidogenesis in pre-luteinized follicles and the de novo synthesis of progesterone from cholesterol due to induction/up-regulation of CYP11A and 3βHSD after the gonadotropin surge in post luteinized follicles.
Diagramatic representation of the steroidogenic pathways in human pre-luteinized follicles (A) and post luteinized follicles (B), demonstrating granulosa dependence on theca cell testosterone steroidogenesis in pre-luteinized follicles and the de novo synthesis of progesterone from cholesterol due to induction/up-regulation of CYP11A and 3βHSD after the gonadotropin surge in post luteinized follicles.


Original file name: Figure 5. 1477-7827-8-117-5-l.jpg
The principle steroid product of luteinized pre-ovulatory granulosa is progesterone, a differentiation triggered by the gonadotropin surge. However, absolute steroid levels are associated with follicular size, not oocyte maturation/ability to fertilize.
Wen et al. Reproductive Biology and Endocrinology 2010 8:117  doi:10.1186/1477-7827-8-117


==Reference==
:'''Links:''' [[Menstrual Cycle]] | [[Ovary Development]] | [[Endocrine System Development]]
===Reference===
<pubmed>20937107</pubmed>| [http://www.rbej.com/content/8/1/117 Reprod Biol Endocrinol.]
<pubmed>20937107</pubmed>| [http://www.rbej.com/content/8/1/117 Reprod Biol Endocrinol.]


 
Wen et al. Reproductive Biology and Endocrinology 2010 8:117  doi:10.1186/1477-7827-8-117
====Copyright====
© 2010 Wen et al; licensee BioMed Central Ltd.  
© 2010 Wen et al; licensee BioMed Central Ltd.  
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Original file name: Figure 5. 1477-7827-8-117-5-l.jpg
{{Footer}}
[[Category:Human]] [[Category:Menstrual Cycle]] [[Category:Endocrine]] [[Category:Ovary]] [[Category:Cartoon]]

Latest revision as of 10:37, 23 May 2016

Ovarian follicular steroid synthesis

Diagramatic representation of the steroidogenic pathways in human pre-luteinized follicles (A) and post luteinized follicles (B), demonstrating granulosa dependence on theca cell testosterone steroidogenesis in pre-luteinized follicles and the de novo synthesis of progesterone from cholesterol due to induction/up-regulation of CYP11A and 3βHSD after the gonadotropin surge in post luteinized follicles.

The principle steroid product of luteinized pre-ovulatory granulosa is progesterone, a differentiation triggered by the gonadotropin surge. However, absolute steroid levels are associated with follicular size, not oocyte maturation/ability to fertilize.

Links: Menstrual Cycle | Ovary Development | Endocrine System Development

Reference

<pubmed>20937107</pubmed>| Reprod Biol Endocrinol.

Wen et al. Reproductive Biology and Endocrinology 2010 8:117 doi:10.1186/1477-7827-8-117

Copyright

© 2010 Wen et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Original file name: Figure 5. 1477-7827-8-117-5-l.jpg



Cite this page: Hill, M.A. (2024, June 15) Embryology Ovarian follicular steroid synthesis.jpg. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/File:Ovarian_follicular_steroid_synthesis.jpg

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