File:Mouse E14.5 gene expression.jpg

Mouse (E14.5) Representative examples of RNA ISH data

The expression categories defined by the annotation summary are illustrated by the following examples.

1. Expression not detected: Rassf1 messenger RNA is not detected at this stage.
2. Homogeneous (non-regional) signal: Wdr68 shows hybridization signal in all tissues and structures.
3. Regionally expressed genes: Crmp1, Mir124, Titf1, and 1300010A20Rik.

• Crmp1 signal is evident in the brain, the V trigeminal ganglion, the spinal cord, and the neural retina.
• miR124 is restricted to the nervous system.
• Titf1 expression is detected in the diencephalon, hypothalamus, telencephalon, thyroid, and lung.
• 1300010A20Rik is an example of a tissue-specific gene with expression limited to the liver.

Complete sets of images for 19,411 genes are available at http://www.eurexpress.org.

Links: Mouse E14.5 gene expression | Titf1 expression | Mouse Development | Eurexpress transcriptome atlas

Reference

<pubmed>21267068</pubmed>| PLoS Biol. | Eurexpress transcriptome atlas

Copyright

© 2010 Diez-Roux et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Citation: Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, et al. (2011) A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo. PLoS Biol 9(1): e1000582. doi:10.1371/journal.pbio.1000582

Original file name: Figure 1. Journal.pbio.1000582.g001.jpg http://www.plosbiology.org/article/slideshow.action?uri=info:doi/10.1371/journal.pbio.1000582&imageURI=info:doi/10.1371/journal.pbio.1000582.g001