File:3D Human pancreatic islet.jpg

Three-dimensional Analysis of Human Pancreatic Islet

• Consecutive sections through an entire adult pancreatic islet labeled for insulin (red) and glucagon (green).
• Images show that insulin (red) and glucagon (green) stained cells are organized into continuous 3-D networks that span the entire islet.
• Sections at both ends show islet profiles with an apparent similar core-mantle structure to that of 40- to 60-μm–diameter islets.
• These consecutive images also reveal that vascular channels were in fact continuous ramified structures that were connected in places with the surrounding islet tissue (arrowheads).
• Image series is representative of 15 different pancreatic islets analyzed from one pancreas.

Scale bar, 50 μm.

Links: Image - Islet Insulin and Glucagon | Endocrine - Pancreas Development

Original file name: FIG. 4. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2857900/figure/F4/ http://diabetes.diabetesjournals.org/content/59/5/1202/F4.large.jpg

Reference

<pubmed>20185817</pubmed>| PMC2857900 | Diabetes.

© 2010 by the American Diabetes Association

Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered. See http://creativecommons.org/licenses/by-nc-nd/3.0/ for details.