UNSW Embryology

International and Australian (text only)

© Dr Mark Hill (2006)

Acknowledgements

Introduction

There are many sources for statistical information relating to Embryology. In particular, childbirth, maternal health, childhood disease and health. As well as international statistics I have included data that specifically relates to Australia. These statisitcs should also be compared with those for Australian Congenital Abnormalities.

World Health Organization (WHO)

World Health Organization (WHO) relating to many human health issues, including fertility, birth control, birthrate and disease.

Some data available locally on Statistical Data page.

Search WHO

Australian Bureau of Statistics

Australian Bureau of Statistics has a publication Australia Now- A Statistical Profile is an easy to read compiled population data, is a comprehensive collection relating to the Australian population as well as other statistical information.

Some data is available locally on Australian population page

National Health and Medical Research Council

The Australian National Health and Medical Research Council prepares recommendations for health care and reports on health. One report on Maternal Deaths during childbirth is particularly relevant.

Search NHMRC

CIA World Factbook 1998

CIA World Factbook 1998 contains small thumbnail information about countries fro amn "American" viewpoint.

Australia Entry

Population data on a country by country basis including male/female ratios.
Some information from 1997 Factbook has been included locally:

The Australian entry (how spies see up).

Birth Data for some comparative countries.

Search Factbook

Congenital Abnormalities

These developmental abnormalities usually involve only small DNA mutations affecting individual or a few genes, two exceptions are the major chromosomal abnormalities usualy trisomy; trisomy 21 (Down syndrome) and trisomy 18 (Edwards syndrome) (also trisomy 9, 13, 15). Note that the occurance of chromosomal abnormalities also increases with increasing maternal age.

There are many pamphlets providing information about prenatal diagnosis (see NSW State Health Publication Checking your baby's health before birth).

A better understanding of abnormal development can also be gained from looking at normal birth statistics

Maternal Derived Abnormalities

Relate to lifestyle, environment and nutrition. Some examples of this form of abnormality are the impact of excess alcohol on neural development (Fetal alcohol syndrome), viral infection (rubella) at a critical stage of development, inadequate dietry folate intake (neural tube defects), effects of prescription drugs (Thalidomide- limb development) and even maternal endocrine function (thyroid development).

In addition to these obvious maternally-derived abnormalities, there is growing evidence that the interuterine environment has a strong influence on later postnatal health. This theory is based on the early statistical analysis of disease/longevity in babies with low birth weights in England by Barker, and has been called the "Barker Hypothesis". (More? Barker Hypothesis)

Finally

Each section of the notes covering early development and specific systems contain references to specific abnormalities (on Page 2 of each notes section). The best source for Australian statistical data is the Australian Institute of Health and Welfare National Perinatal Statistics Unit, UNSW which publishes "Congenital Malformations Australia" every 2 years. Be aware that some congenital abnormalities, by their nature, affect multiple systems. In the USA, the Center for Disease Control (CDC) keeps and publishes relevant statistical information. A very difficult issue in abnormal development are the many different Ethical implications.

This current page is a link to Normal and Abnormal Development and Population Data.

Where to Next?

You should look at normal development. Development Notes

Alternatively, go on to look at Systematic Development of organs and tissues.

Glossary of Terms

A |B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W |X | Y | Z

Quick Links

Finally

For those wanting to see dynamic processes of development (and have a reasonably quick connection) then the Movies pages are good for watching changes occur.

Other Embryos

The study of human development has relied extensively on studying the process in other model animals. For those wanting to see the process of development in other species then the other embryos pages are a good start.

UNSW Embryology ISBN: 0 7334 2321 3

UNSW CRICOS Provider Code No. 00098G