UNSW Embryo- Development of the Nervous System. Selected References Back to Neural Notes selected refs page 1 / page 2 Articles | Reviews | Books Links: Page 2 Page 1 PubMed Link About PubMed Note: A Selected List of References for Neural Development from PubMed March 1999. It was too difficult to keep neural development to one page so I have selected a few current Articles below and given a short description of the relevance to specific aspects of neural development. Internet access computers will be able to get abstract directly from PubMed (when available) by clicking Abstract below.

Articles Notch/Delta  Primary neurogenesis in Xenopus embryos regulated by a homologue of the Drosophila neurogenic gene Delta. Chitnis A, Henrique D, Lewis J, Ish-Horowicz D, Kintner C Nature 1995 Jun 29;375(6534):761-6 Abstract | Related Articles MH- This article linked the fly neurogenic gene to blastula neural development in "higher" organisms. The key is a receptor mediated lateral inhibition, which generates bilaterally paired 3 streaks of neural progenitor cells. This occurs on the ectoderm prior to neural tube formation, showing neural specification occurs prior to the actual process of neural groove, neural tube formation. Each streak represents a different population of neurons (in the spinal cord: sensory, interneuron, motor) Other neural plate issues Establishment and maintenance of the border of the neural plate in the chick: involvement of FGF and BMP activity. Streit A, Stern CD Mech Dev 1999 Apr;82(1-2):51-66 Abstract | MH- A related issue about how the neural plate may be established and maintained. FGF = fibroblast growth factor BMP = bone morphogenic protein An early phase of embryonic Dlx5 expression defines the rostral boundary of the neural plate. Yang L, Zhang H, Hu G, Wang H, Abate-Shen C, Shen MM J Neurosci 1998 Oct 15;18(20):8322-30 Abstract | MH- A related issue about how the rostral end of the neural plate may be defined. Dlx = Distal-less, a homeobox gene Reviews   Books