UNSW Embryology

Rabbit Development - Early

© Dr Mark Hill (2008)

Acknowledgements

Introduction

This page describes the early development of the rabbit embryo.

Page Links: Introduction | Development Overview | Carnegie Stages Comparison | Rabbit Placentation | Fetal Weight Growth | WWW Links | References | Glossary

Gastrulation

Idkowiak J, Weisheit G, Plitzner J, Viebahn C.    [See Related Articles] Hypoblast controls mesoderm generation and axial patterning in the gastrulating rabbit embryo. Dev Genes Evol. 2004 Dec;214(12):591-605. "The epiblast shows a stage-dependent and topographically restricted susceptibility to express Brachyury, a T-box gene pivotal for mesoderm formation, and to transform into (histologically proven) mesoderm. These results confirm for the mammalian embryo that the anterior-posterior axis of the conceptus is formed first as a molecular prepattern in the hypoblast and then irrevocably fixed, under the control of signals secreted from the hypoblast, by epithelio-mesenchymal transformation (primitive streak formation) in the epiblast."

Development Overview

After mating ovulation occurs 10 hours later.

Blastocyst apposition and attachment (day 6.5).

Carnegie Stages Comparison

Species	Stage	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23
Human	Days	20	22	24	28	30	33	36	40	42	44	48	52	54	55	58
Rabbit	Days	8	8.5	9.5	10.5	11	12	12.5	13.5	14	14.5	15.5	16	16.5	17	18

Reference: Edwards, The external development of the rabbit and rat embryo. Advances in teratology, Vol 3, Woollam(ed), Academic Press, NY (1968)

 

Fetal Weight Growth

Overview of fetal and placental weight growth in Rabbits (Graph: Hammond and Marshall, 1925)

WWW Links

Food and Agriculture Organization of the United Nations The Rabbit - Husbandry, Health and Production | Chapter 3 REPRODUCTION (FAO Animal Production and Health Series No. 21)

DebMark Rabbit Education Resource Raising Rabbits - The Basics

References

Links: Reviews | Articles | Online Textbooks | Search Textbooks | Search PubMed | Glossary

PubMed

Reviews

• Lee KY, DeMayo FJ.    [See Related Articles] Animal models of implantation. Reproduction. 2004 Dec;128(6):679-95.

Articles

• Idkowiak J, Weisheit G, Plitzner J, Viebahn C.    [See Related Articles] Hypoblast controls mesoderm generation and axial patterning in the gastrulating rabbit embryo. Dev Genes Evol. 2004 Dec;214(12):591-605.
• Idkowiak J, Weisheit G, Viebahn C.    [See Related Articles] Polarity in the rabbit embryo. Semin Cell Dev Biol. 2004 Oct;15(5):607-17. Review. Erratum in: Semin Cell Dev Biol. 2005 Feb;16(1):149-50.
• Viebahn C, Stortz C, Mitchell SA, Blum M.    [See Related Articles] Low proliferative and high migratory activity in the area of Brachyury expressing mesoderm progenitor cells in the gastrulating rabbit embryo. Development. 2002 May;129(10):2355-65.
• Yan LY, Shi LH, Sheng HZ, Liu SZ, Huang JC, Zhu ZY, OuYang YC, Lei ZL, Song XF, Sun QY, Chen DY.    [See Related Articles] Dynamic changes in NuMA and microtubules in monkey-rabbit nuclear transfer embryos. Front Biosci. 2006 May 1;11:1892-900.
• Ogonuki N, Inoue K, Miki H, Mochida K, Hatori M, Okada H, Takeiri S, Shimozawa N, Nagashima H, Sankai T, Ogura A.    [See Related Articles] Differential development of rabbit embryos following microinsemination with sperm and spermatids. Mol Reprod Dev. 2005 Nov;72(3):411-7.
• Enders AC, Schlafke S.    [See Related Articles] Penetration of the uterine epithelium during implantation in the rabbit. Am J Anat. 1971 Oct;132(2):219-30.

Search PubMed

Search Feb 2006 "early rabbit embryo development" 21572 reference articles of which 1191 were reviews.

Search PubMed: term = early+rabbit+embryo+development | term = rabbit+gastrulation

Glossary of Terms

A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z

Quick Links

Development Notes ----------------- Menstrual Cycle Week 1 Week 2 Week 3 Week 4 Placenta Serial Images Genes/DNA Molecular Dev Abnormal Dev Postnatal Dev Notes Index

System Notes ----------------- Heart/Cardiovascular Respiratory Coelomic cavity Gastrointestinal Tract Head and Neck Neural Neural Crest Eye Ear Nose Endocrine Urogenital Musculoskeletal Integumentary

Movies ----------------- Embryo Growth Ultrasound Week 1 Week 2 Week 3 Week 4 Stage 13/14 Stage 22 Neural Head and Neck Heart Vasculature Gastrointestinal Urogenital Other Embryos Larsen Internet

Other Embryos ----------------- Chicken Fly Frog Guinea Pig Mouse Rabbit Rat Worm Zebrafish

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