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TWINNING, MONOZYGOTIC

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276410 TWINNING, MONOZYGOTIC

table OF CONTENTS

 

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2 MEDLINE Citations

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TEXT

Although the frequency of monozygotic twinning has been said to be uninfluenced by genetic factors, Harvey et al. (1977) reported 10 families with multiple pairs of monozygotic twins and suggested that the question should be reexamined. Both fathers and mothers were represented among MZ twin parents of MZ twins. Shapiro et al. (1978) reported a kindred with 4 sets of monozygotic twins and favored autosomal dominant inheritance for a subset of monozygotic twins. Derom et al. (1987) found a significant increase in the frequency of zygotic splitting producing monozygotic twins and triplets after artificial induction of ovulation. This may be the first identified biological mechanism influencing the monozygotic twinning rate. 30 MEDLINE Neighbors


REFERENCES

1. Derom, C.; Vlietinck, R.; Derom, R.; Van den Berghe, H.; Thiery, M. :
Increased monozygotic twinning rate after ovulation induction. Lancet I: 1236-1238, 1987.
PubMed ID : 2884372

 

2. Harvey, M. A. S.; Huntley, R. M. C.; Smith, D. W. :
Familial monozygotic twinning. J. Pediat. 90: 246-248, 1977.
PubMed ID : 556630

 

3. Shapiro, L. R.; Zemek, L.; Shulman, M. J. :
Genetic etiology for monozygotic twinning. Birth Defects Orig. Art. Ser. XIV(6A): 219-222, 1978.

 


CLINICAL SYNOPSIS

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CREATION DATE

Victor A. McKusick : 6/4/1986


EDIT HISTORY

mimadm : 3/12/1994
supermim : 3/17/1992
supermim : 3/20/1990
ddp : 10/27/1989
marie : 3/25/1988
root : 6/16/1987

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