This page shows the selected Carnegie stage 22 embryo images and external Histology links that relate to cardiovascular development. These selected images are regions within the heart at a higher magnification of the Stage 22 embryo. The small image excerpts show specific features, which can then be observed in the linked complete sections.
Page Links: Introduction | Selected Serial Sections | Selected Serial Section table (Stage 22) | WWW Histology |
These are scaled image excerpts, click on image or section name to see full size section for details.
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D4 t/s Chest (valves, atrium, coronary sinus) |
D4 Heart region |
D5 Heart valves |
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D7 t/s Chest (heart atria and ventricles) |
E1 Heart (atrial septation overview) |
E2 Heart Valves (atrial septation detail) |
Links to related WWW sites with Histological
images for Cardiovascular and Blood system.
Note that all internet links change with time if
link does not work use text shown to search WWW.
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The heart is therefore one of the earliest differentiating and functioning organs. Most texts will separate heart development from vascular development in order to simplify their descriptions of cardiovascular development, though the 2 are functionally and embryologically connected.
The heart develops from cardiogenic mesoderm that originally lies above the cranial end of the developing neural tube. Enlargement of the cranial neural fold brings this region ventrally to its correct anatomical position. The original paired cardiac tubes fuse, with the "ventricular" primordia initially lying above the "atria". Growth of the cardiac tube flexes it into an "S-shape" tube, rotating the "ventricles" downward and pushing the "atria" upward. This is then followed by septation, a complex process which converts this simple tube into a four chambered heart. A key part of this process is the separation of cardiac outflow (truncus arteriosus) into a separate pulmonary and aortic arch outflow. During embryonic development there is extensive remodelling of the initially r/l symetrical cardiovascular system and a contribution from the neural crest to some vessels.
Please email Dr Mark Hill if you wish to make a comment about this current project.
