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UNSW Embryology

Cardiovascular System Development- Stage 13/14

© Dr Mark Hill (2009)

Acknowledgements

High pressure pathway from the Ventricles into the Aortic System

G7 An overview of blood flow through the embryo of oxygenated blood. Note the umbilical artery and veins anastomose within the chorion of the placenta, there is no direct connection of maternal and fetal blood.

Maternal Blood


umbilical vein
liver
anastomosis
ductus venosus
sinus venosus
atria ventricles
truncus arteriosus
aortic sac
aortic arches
dorsal aorta
pair of umbilical arteries

Maternal Blood

High pressure pathway from the ventricles into the aortic system.

D7: Apex of left ventricle: spongy network of endocardium; a small dorsal cavity (part of the intraembryonic coelom which will become the pericardial cavity - no pericardium yet); mesenchymal jelly of body wall.

D6,D5: Tip of right ventricle; left ventricle; I-E coelom; liver, with its ventral transverse border, the septum transversum.

D2: Trabeculae of L and R ventricles; interventricular septum; interembryonic coelom; sinus venosus caudal tip of part of left atrium = L auricular appendage.

Dl: Endocardial jelly at dorsal wall of interventricular septum.

C7: Ventricles forming interventricular septum (muscular portion); dorsal endocardial jelly communication of L auricle and L atrium; R atrium; R auricle.

C6: Aperture in interatrial septum, the ostium (foramen) primum. L and R atrioventricular canals. Note the L auricle is not separated from L atrium, the plane of section has caught the wall fold at the region where the auricle connects.

C5: Communication of L auricle with left atrium.

C4: Transition from R ventricle to the outflow tract, including the truncus arteriosus and complete interatrial septum (cf. C5).

C3: Truncus arteriosus. Atria. Right venous valve in R atrium.

 

 

C7-C3: Return to C7 and proceed to C3, noting how left ventricular blood has to pass obliquely across right ventricle to exit from heart via the outflow tract and truncus arteriosus.

C2, C1 Truncus arteriosus shifting to midline. Jelly and mantle of the truncus. Cranial end of R venous valve. Note also extent of I-E coelom; thin body wall.

B7-B5: Attachment of truncus arteriosus to ventral body wall and to dorsal roof of intra embryonic coelom. Note the primordium of the transverse pericardial sinus in B6, caudal to the attachment of the truncus.

B5: Entry of truncus arteriosus into B4aortic sac, completely embedded in pharyngeal arch mesectoderm.

Observe position of aortic sac in relation to pharynx and pharyngeal arches. 4th pharyngeal arch artery on left.

B5 small "6th" pharyngeal arch artery either side of the laterally-compressed pharynx.

B3: Cranial end of aortic sac. 4th pharyngeal arch arteries and emerging 3rd pharyngeal arch artery. Note dark thyroid primordium ventral to origin of 3rd arch arteries.

 B2: (lst and 2nd pharyngeal arch arteries not seen. 3rd arch arteries. Bilaterally, communication of 4th arch artery (at sides of pharynx) with dorsal aorta.

B1: 3rd arch arteries. Dorsal aortae. (Superior cardinal veins lateral to aortae).

A7: On left side, communication of 3rd arch artery with aorta (i.e. occurring cranial to the 4th arch communication). From here on the arterial blood is distributed through fine branches to vessels outside the brain (pial plexus).

Next- caudal path of the arterial blood

Next page for embryonic blood flow

caudal path of the arterial blood

Serial Section table (Stage 13/14)

Stage 13/14 Embryo (Pig)

A1

A2

A3

A4

A5

A6

A7

B1

B2

B3

B4

B5

B6

B7

C1

C2

C3

C4

C5

C6

C7

D1

D2

D3

D4

D5

D6

D7

E1

E2

E3

E4

E5

E6

E7

F1

F2

F3

F4

F5

F6

F7

G1

G2

G3

G4

G5

G6

G7

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