Movie shows the migration of DiI-labeled neural crest cells towards the branchial
arches as the embryo undergoes its rotation to one side. Notice how the cells
emigrate in streams which spread out to cover a subregion of the periphery.
Duration: 12 hrs.
Time interval between images: 3 min.
* In all the movies, each image represents 10 confocal sections separated by 10 microns each, projected onto 1 image. Movies provided as supplementary material to original poblication.
Also see reference below and additional movies.
Quicktime movie: movie1.qt (6.9 Mb)
in new window.Neural crest cells leave from near the midbrain (m), midbrain/hindbrain boundary (m/h) and rostral rhombomeres (r1 and r2) and spread out to cover a wide region adjacent to the neural tube.
Duration: 7 hrs
Time interval between images: 3 min
Quicktime movie: movie2.qt (5.1 Mb)
in new window.Neural crest cells from r3, r4 and r5 contribute to the stream exiting adjacent
to r4. Duration: 3 hrs
Time interval between images: 3 min
Quicktime movie: movie3.qt (5.7 Mb)
in new window.1. Paul M. Kulesa and Scott E. Fraser In ovo time-lapse analysis of chick hindbrain neural crest cell migration shows cell interactions during migration to the branchial arches. Development Vol 127/06 (2000)
2. UNSW Embryology Neural Crest Notes are a series of notes describing the development of neural crest and the many cell types it forms.
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These wonderful research movies allows the tracking of labelled neural crest cells in the living developing chicken embryo. These types of studies show the value of animal (chicken) models of development, it would be very difficult to do a similar study in a mammal (placental animal) as access to teh embryo is very difficult.
Note these movies are very large and will take some time to download if viewed from internet and not CD.
Neural crest cells arise initially at the edge of the neural plate and distribute (migrate) throughout the embryo, differentiating into many different cell types in the embryo.
This specific movie shows neural crest migration in the head region, where it contributes to many head structures. For more information see Neural Crest Notes.
UNSW Embryology has many movies to show some of the dynamic changes that occur during embryonic development. These have been grouped together on separate pages (listed in righthand menu) that can be also be opened from a pull down menu on each page.
Internet users note that some of these movies are large and will take some time to download depending on your connection speed.
There also an about movies page which has technical details and terms listed.
Both Mac and PC computers require the Quicktime plug-in to be present in your browser or on your computer.
CD users can find Quicktime on the CD or the latest version can be downloaded from here Quicktime
Please email Dr Mark Hill if you wish to make a comment about this current project.