UNSW Embryology

Neural Movies: Movie Neural Cell Migration

© Dr Mark Hill (2004)

Acknowledgements

Movement of Nuclei in Early Stages of Neural Rod Formation

Quicktime: pbio.0050069.sv001.mov (712 Kb)

Time-lapse analysis from early tailbud stage to 5-somite stage, dorsal view, anterior to the left. Mosaic labelling of nuclei with RFP (red) in her5pac:egfp (green) transgenic embryo.

"Study examined gene expression patterns in an area of the neural plate that later forms the forebrain to show that well-defined cell populations will develop into specific forebrain regions, such as the prethalamus, thalamus, hypothalamus, and epithalamus. We then tested whether these early neural plate subterritories are fully committed to a particular forebrain identity. We found that precursors of the prethalamus are not replaceable by other neighbouring cells, because ablation of these cells results in loss of prethalamus development. Moreover, when prethalamus precursors were moved into the environment of the presumptive hindbrain, the cells still pursued their prethalamic differentiation program."

Reference

Staudt N, Houart C. The Prethalamus Is Established during Gastrulation and Influences Diencephalic Regionalization. PLoS Biol. 2007 Mar 6;5(4):e69 PLoS Biology Link

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Human Embryology Neural Movies

Notochord (179Kb)
Notochord (111Kb)
Neural Plate (468Kb)
Neurulation (468Kb)
Secondary Neurulation (561Kb)

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