This movie shows the dynamic nature of developing neural cells in the frog embryo.
Neural movie kindly provided by Lance Davidson.
A scattered labeled sheet of cells migrate to the right toward the midline (a line from top to bottom to the right of the labeled patch) beneath the recently fused epidermis. Over the course of the timelapse sequence the labeled cells converge on the midline. During this convergence the sheet also extends along the axis. The contiguously labeled sheet extends and is broken apart as unlabeled cells intercalate between labeled cells. Such sequences are characteristic of "convergent extension" movements.
L. A. Davidson and R. E. Keller Neural tube closure in Xenopus laevis involves medial migration, directed protrusive activity, cell intercalation, and convergent extension Development 126: 4547-4556 (1999)
Notochord (179Kb)
Notochord (111Kb)
Neural Plate (468Kb)
Neurulation (468Kb)
Secondary Neurulation (561Kb)
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Neural movie kindly provided by Lance Davidson.
UNSW Embryology has many movies to show some of the dynamic changes that occur during embryonic development. These have been grouped together on separate pages (listed in righthand menu) that can be also be opened from a pull down menu on each page.
Internet users note that some of these movies are large and will take some time to download depending on your connection speed.
Both Mac and PC computers require the Quicktime plug-in to be present in your browser or on your computer.
CD users can find Quicktime on the CD or the latest version can be downloaded from here Quicktime
Please email Dr Mark Hill if you wish to make a comment about this current project.