References- Cell
Cycle
- Pumin Zhang The cell cycle and
development: redundant roles of cell cycle
regulators Current Opinion in Cell
Biology 1999, 11:655-662.
- excellent recent review on liver
development. (source for references cited
below)
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The retinoblastoma protein and cell cycle
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Cdk inhibitors in development and
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Regulation of cyclin E transcription by E2Fs
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Cell cycle regulation of the murine cyclin E
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Regulation of the cyclin E gene by
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The regulation of E2F by pRb-family
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2245&endash;2262.
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Retinoblastoma protein recruits histone
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Rb interacts with histone deacetylase to
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Retinoblastoma protein represses
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Histone acetylation in chromatin structure
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Interaction of myogenic factors and the
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Skeletal muscle cells lacking the
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Rb binds c-Jun and activates
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Retinoblastoma protein positively regulates
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Jr:
Stable binding to E2F is not required for the
retinoblastoma protein to activate
transcription, promote differentiation, and
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The retinoblastoma protein and BRG1 form a
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Functional interactions between the
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A role for retinoblastoma protein in
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The retinoblastoma-susceptibility gene
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Cloning and expression of human TAFII250: a
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The TAF(II) 250 subunit of TFIID has histone
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Shared role of the pRB-related p130 and p107
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Targeted disruption of p107: functional
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Lugt NM, van der Valk M, Hooper ML, Berns A, te
Riele H:
Requirement for a functional Rb-1 gene in
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328&endash;330.
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Effects of an Rb mutation in the
mouse.
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Mice deficient for Rb are nonviable and show
defects in neurogenesis and
haematopoiesis.
Nature 1992, 359:
288&endash;294.
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Phillips RA, Gallie BL:
pRb controls proliferation, differentiation,
and death of skeletal muscle cells and other
lineages during embryogenesis.
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3051&endash;3064.
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Yamasaki L, Jacks T:
Mutation of E2F-1 suppresses apoptosis and
inappropriate S phase entry and extends survival
of Rb-deficient mouse embryos.
Mol Cell 1998, 2:
293&endash;304.
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Lassar AB:
pRb is required for MEF2-dependent gene
expression as well as cell-cycle arrest during
skeletal muscle differentiation.
Curr Biol 1999, 9:
449&endash;459.
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EN:
Cooperative activation of muscle gene
expression by MEF2 and myogenic bHLH
proteins.
Cell 1995, 83:
1125&endash;1136.
- Parker SB, Eichele G, Zhang P, Rawls A,
Sands AT, Bradley A, Olson EN, Harper JW,
Elledge SJ:
p53-independent expression of
p21Cip1 in muscle and other
terminally differentiating cells.
Science 1995, 267:
1024&endash;1027.
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Rhee J, Hannon GJ, Beach D, Lassar AB:
Correlation of terminal cell cycle arrest of
skeletal muscle with induction of p21 by
MyoD.
Science 1995, 267:
1018&endash;1021.
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K:
MyoD-induced expression of p21 inhibits
cyclin-dependent kinase activity upon myocyte
terminal differentiation.
Mol Cell Biol 1995, 15:
3823&endash;3829.
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Leder P:
Mice lacking p21CIP1/WAF1 undergo
normal development, but are defective in G1
checkpoint control.
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675&endash;684.
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Beach D, Jacks T, Hannon GJ:
Radiation-induced cell cycle arrest
compromised by p21 deficiency.
Nature 1995, 377:
552&endash;557.
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JW, Elledge SJ:
p21CIP1 and p57KIP2
control muscle differentiation at the myogenin
step.
Genes Dev 1999, 13:
213&endash;224.
- Matsuoka S, Edwards MC, Bai C, Parker S,
Zhang P, Baldini A, Harper JW, Elledge SJ:
p57KIP2, a structurally distinct
member of the p21CIP1 Cdk inhibitor
family, is a candidate tumor suppressor
gene.
Genes Dev 1995, 9:
650&endash;662.
- Zhang P, Liegeois NJ, Wong C, Finegold M,
Hou H, Thompson JC, Silverman A, Harper JW,
DePinho RA, Elledge SJ:
Altered cell differentiation and
proliferation in mice lacking p57KIP2
indicates a role in Beckwith&endash;Wiedemann
syndrome.
Nature 1997, 387:
151&endash;158.
- Yan Y, Frisen J, Lee MH, Massague J,
Barbacid M:
Ablation of the CDK inhibitor
p57Kip2 results in increased
apoptosis and delayed differentiation during
mouse development.
Genes Dev 1997, 11:
973&endash;983.
- Venuti JM, Morris JH, Vivian JL, Olson EN,
Klein WH:
Myogenin is required for late but not early
aspects of myogenesis during mouse
development.
J Cell Biol 1995, 128:
563&endash;576.
- Schneider JW, Gu W, Zhu L, Mahdavi V,
Nadal-Ginard B:
Reversal of terminal differentiation mediated
by p107 in Rb-/- muscle
cells.
Science 1994, 264:
1467&endash;1471.
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Ong L, Seth PK, Dotto GP:
Inhibitory function of
p21Cip1/WAF1 in differentiation of
primary mouse keratinocytes independent of cell
cycle control.
Science 1998, 280:
1069&endash;1072.
- Zhang JM, Wei Q, Zhao X, Paterson BM:
Coupling of the cell cycle and myogenesis
through the cyclin D1- dependent interaction of
MyoD with Cdk4.
EMBO J 1999, 18:
926&endash;933.
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DePinho RA:
p53-dependent apoptosis produced by
Rb-deficiency in the developing mouse
lens.
Nature 1994, 371:
72&endash;74.
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Lens differentiation in vertebrates. A review
of cellular and molecular features.
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134&endash;153.
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Induction of the eye lens.
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137&endash;149.
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Nevins J:
Distinct roles for E2F proteins in cell
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Proc Natl Acad Sci USA 94:
7245&endash;7250.
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Alternative reading frames of the INK4A
tumour supressor gene encode two unrelated
proteins capable of inducing cell cycle
arrest.
Cell 1995, 83:
993&endash;1000.
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Silverman A, Alland L, Chin L, Potes J, Chen K,
Orlow I, Lee HW, Cordon-Cardo C, DePinho RA:
The Ink4a tumour suppressor gene product,
p19Arf, interacts with MDM2 and neutralizes
MDM2's inhibition of p53.
Cell 1998, 92:
713&endash;723.
- Zhang Y, Xiong Y, Yarbrough WG:
ARF promotes MDM2 degradation and stabilizes
p53: ARF-INK4a locus deletion impairs both the
Rb and p53 tumour suppression pathways.
Cell 1992, 92:
725&endash;734.
- Zhang P, Wong C, DePinho RA, Harper JW,
Elledge SJ:
Cooperation between the Cdk inhibitors
p27KIP1 and p57KIP2 in the
control of tissue growth and
development.
Genes Dev 1998, 12:
3162&endash;3167.
- Fero ML, Rivkin M, Tasch M, Porter P, Carow
CE, Firpo E, Polyak K, Tsai LH, Broudy V,
Perlmutter RM et al.:
A syndrome of multiorgan hyperplasia with
features of gigantism, tumorigenesis, and female
sterility in p27Kip1-deficient
mice.
Cell 1996, 85:
733&endash;744.
- Kiyokawa H, Kineman RD, Manova-Todorova KO,
Soares VC, Hoffman ES, Ono M, Khanam D, Hayday
AC, Frohman LA, Koff A:
Enhanced growth of mice lacking the
cyclin-dependent kinase inhibitor function of
p27Kip1.
Cell 1996, 85:
721&endash;732.
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Inoue T, Shishido N, Horii I, Loh DY:
Mice lacking p27Kip1 display
increased body size, multiple organ hyperplasia,
retinal dysplasia, and pituitary tumors.
Cell 1996, 85:
707&endash;720.
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Schoonhoven R, Chen Kiang S, Su L, Xiong Y:
CDK inhibitors p18INK4c and
p27Kip1 mediate two separate pathways
to collaboratively suppress pituitary
tumorigenesis.
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2899&endash;2911.
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Cancer cell cycles.
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Roberts JM, Pagano M:
Human cyclin E, a nuclear protein essential
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Cyclin-dependent kinase control of centrosome
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Proc Natl Acad Sci USA 1999, 96:
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Cyclin-dependent kinase 2 (Cdk2) is required
for centrosome duplication in mammalian
cells.
Curr Biol 1999, 9:
429&endash;432.
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JL, Sluder G:
Requirement of Cdk2-cyclin E activity for
repeated centrosome reproduction in
Xenopus egg extracts.
Science 1999, 283:
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Elledge SJ, Weinberg RA:
Cyclin D1 provides a link between development
and oncogenesis in the retina and
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621&endash;630.
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Medema RH, Li T, Weinberg RA, Sicinski P:
Rescue of cyclin D1 deficiency by knockin
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767&endash;777.
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Mammalian G1 cyclins.
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Galbreath EJ, Boden G, Reddy EP, Barbacid M:
Loss of Cdk4 expression causes
insulin-deficient diabetes and Cdk4 activation
results in beta-islet cell hyperplasia.
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SB, Gardner H, Park MY, Robker RL, Richards
JS, McGinnis LK, Biggers JD et al.:
Cyclin D2 is an FSH-responsive gene
involved in gonadal cell proliferation and
oncogenesis.
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