UNSW Embryology
Molecular Development- MyoD1	Embryology Home Page
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Page LinksIntroduction ReferencesAbout Notes Other pages: | Molecular Development | Axes Development | Neural Axes | Limb Axes	Back to Molecular Development
Introduction Within the somite expression of MyoD in the dorsomedial quadrant of patterns these cells to be muscle. MyoD is a basic helix-loop-helix type of transcription factor that binds DNA as a dimer with other bHLH proteins (eg ITF-2). Its actions are inhibited by binding with ID. from myotome dorsomedial quarter- epaxial myotome dorsal epimere (erector spinae) dorsolateral quarter- hypaxial myotome ventral hypomere (3 primary muscle layers) different at neck, thorax and abdomen
Database Entry Links Genbank | Swiss-protein Human Genbank Entries   Help Locus Link Help Page Link code PubMed OMIM RefSeq GenBank UniGene Variation top of page Swiss-Protein NiceProt View MYOBLAST DETERMINATION PROTEIN 1 found in SWISS-PROT: 32
References Brand-Saberi B, et al.           [See Related Articles] Genetic and epigenetic control of muscle development in vertebrates. Cell Tissue Res. 1999 Apr;296(1):199-212. Review. PMID: 10199980; UI: 99216353. Dietrich S.           [See Related Articles] Regulation of hypaxial muscle development. Cell Tissue Res. 1999 Apr;296(1):175-82. Review. PMID: 10199977; UI: 99216350. Kalcheim C, et al.           [See Related Articles] Myotome formation: a multistage process. Cell Tissue Res. 1999 Apr;296(1):161-73. Review. PMID: 10199976; UI: 99216349. Blagden CS, et al.           [See Related Articles] Extrinsic influences on limb muscle organisation. Cell Tissue Res. 1999 Apr;296(1):141-50. Review. PMID: 10199974; UI: 99216347.
Lecture Notes Please note that these notes only relate to the Anat 3311 Course. This section is not completely available, as I have been unable to transfer all my Lecture notes and research material in time for the deadline. This will be available in later versions. Early Development Lecture Simple pictures illustrating the early events of fertilization. Spinal Cord Development Figures and text relating to early events of spinal cord formation. Sex Determination Text relating to the molecular events of sex determination in the embryo. Polarity Concepts A short comparison of establishing positional information in embryos. Antennapedia The fly mutation that opened the field of Hox Genes and the conservation of pattern formation control mechanisms between species in embryonic development.
External WWW Search This current page has additional windows that allow searching of OMIM Morbid Map and OMIM Gene Map and access to other External WWW Search pages (Medical dictionaries, glossaries, chemicals and drugs). In the DNA Notes there is a window to search the Human Genome by keyword and also to search for a specific species classification. In the DNA Notes there is also a page with 3 search windows for Nucleotide Sequence, Protein Sequence and Biomolecule 3D Structure from NCBI. In the Chemical Notes there is a window to search a Material Safety Data Sheet database for a specific chemical and its associated hazard.
About Notes Notes from the Embryology Program compiled and written by Dr Mark Hill. This updated section of notes is still being developed Mar2000 and is not yet complete. Note that reference lists are only relevant to the date of the original search.	Links Serial Sections Homepage Human Homepage Pig Homepage
m.hill@unsw.edu.au Date Last Modified: 19/3/99 This site maintained by Dr M. Hill