UNSW Embryology

Development- Sudden Infant Death Syndrome

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Related Pages: Abnormal Development- Smoking

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Page 5 | Maternal Factors
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Introduction

Smoking and Pregnancy

  • Smoking doubles the risk of having a low-birthweight baby and significantly increases the rate of perinatal mortality and several other adverse pregnancy outcomes.
  • The mean reduction in birthweight for babies of smoking mothers is 200 g.
  • High quality interventions to help pregnant women quit smoking produce an absolute difference of 8.1% in validated late-pregnancy quit rates.
  • If abstinence is not achievable, it is likely that a 50% reduction in smoking would be the minimum necessary to benefit the health of mother and baby.
  • Healthcare providers perform poorly in antenatal interventions to stop women smoking. Midwives deliver interventions at a higher rate than doctors.
  • The efficacy of nicotine replacement therapy has not been established in pregnancy. Currently, its use should only be considered in women smoking more than 10 cigarettes per day who have made a recent, unsuccessful attempt to quit and who are motivated to quit.
  • Relapse prevention programs have shown little success in the postpartum period.

Data from: Quitting smoking in pregnancy Raoul A Walsh, John B Lowe, Peter J Hopkins (MJA 2001; 175: 320-323)

See also- Abnormal Development- Smoking

NHMRC Publication- Risk factors associated with SIDS (Oct 1991)

  • The possible causes of Sudden Infant Death Syndrome (SIDS), sometimes called cot death, are still not known. However, population studies have identified risk factors that may contribute to SIDS. Risk factors that parents may be able to do something about include; sleeping posture, feeding practices and passive smoking.
  • Recent research suggests that babies who sleep on their stomach may have a higher risk of SIDS. The NHMRC recommends that babies should generally sleep on their side or on their back. If on their side, the lower arm should be placed well forward so that babies cannot roll on their stomach. Some babies may need to sleep on their stomach for medical reasons. Parents should discuss with their doctor whether this applies to their baby.
  • Breast feeding may reduce the risk of SIDS. Breast milk is the best food for babies. Babies should be breast fed if at all possible.
  • Passive smoking is associated with an increased risk of SIDS. NHMRC recommends pregnant mothers should not smoke. This is particularly important during pregnancy and in the baby's first year. Others should not smoke near the baby.
  • These risk factors alone do not cause SIDS and it is extremely rare for babies exposed to them to die of SIDS. However, following the above advice may help reduce the number of SIDS deaths. Research is continuing to search for the basic cause of SIDS.
  • There has been concern in the community that immunisation is associated with SIDS. There is no scientific evidence to support this belief. No association of immunisation with SIDS has been documented.

Excerpt from NHMRC Statement

The Australian NHMRC (1988) recommends neonates be assessed for follow-up care under the following conditions.

(see the NHMRC WWW Page)

  • Birthweight less than 1500g or gestational age less than 32 weeks
  • Small-for-gestational-age neonates
  • Perinatal asphyxia
  • Apgar score less than 3 at 5 minutes
  • clinical evidence of neurological dysfunction
  • delay in onset of spontaneous respiration for more than 5 minutes and requiring mechanical ventilation
  • Clinical evidence of central nervous system abnormalities ie., seizures, hypotonia
  • Hyperbilirubinaemia of greater than 350umol/l in full term neonates
  • Genetic, dysmorphic or metabolic disorders or a family history of serious genetic disorder
  • Perinatal or serious neonatal infection including children of mothers who are HIV positive
  • Psychosocial problems eg., infants of drug-addicted or alcoholic mothers.

WWW Links 

SIDS Links USA

For Normal Childhood Development see Publications (or NHMRC WWW Page)

About Notes

  • Notes from the Embryology Program compiled and written by Dr Mark Hill.
  • Note Links to OMIM Entries are copies of originals for computers without internet access. Computers with internet access can directly access the database.

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m.hill@unsw.edu.au
Date Last Modified: 17/9/2001
This site maintained by Dr M. Hill