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UNSW Embryology

Prenatal Diagnosis - Chorionic Villus Sampling

© Dr Mark Hill (2008)

Acknowledgements

Introduction

Chorionic Villus Sampling test is done in the 10th to 12th week after the first day of the mother's last menstrual period.

Chorionic Villus Sampling

The test is done by looking at cells taken from the chorionic membrane or placenta. No anaesthetic is required, and a test result is usually available in two to three weeks.

When the test is carried out by an obstetrician experienced in the technique, the risk of miscarriage related to the test is about 2 %. (Modified from: Checking your baby's health before birth. State Health Publication Number (PA) 94-090)

Page Links: Introduction | Some Recent Findings | References | WWW Links | Glossary

Some Recent Findings

Wolstenholme J, Emslie JB, Connors S. Association of Clinical Cytogeneticists chorion villus sampling database 1987-2000. Prenat Diagn. 2006 May;26(5):420-7. ACC CVS database

WWW Links

Natinal Library of Medicine (USA)

Clinical Trial (USA) - chorionic villi sampling Invasive Prenatal Testing Decisions in Pregnancy After Infertility

Medline Plus - Chorionic villus sampling

NIH - genetic testing

Commercial Information

The Merck Manual- Tests for Genetic Disorders

Health Central- Information about CVS

Obstetrics-Gynecology Commercial Information

References

Reviews | Articles | Search NCBI Bookshelf | Search PubMed | Glossary

Reviews

Evans MI, Wapner RJ. Invasive prenatal diagnostic procedures 2005. Semin Perinatol. 2005 Aug;29(4):215-8.

Ball RH. Invasive fetal testing. Curr Opin Obstet Gynecol. 2004 Apr;16(2):159-62.

Weisz B, Rodeck CH. Invasive diagnostic procedures in twin pregnancies. Prenat Diagn. 2005 Sep;25(9):751-8.

Articles

Savva GM, Morris JK, Mutton DE, Alberman E. Maternal age-specific fetal loss rates in Down syndrome pregnancies. Prenat Diagn. 2006 Jun;26(6):499-504.

Wolstenholme J, Emslie JB, Connors S. Association of Clinical Cytogeneticists chorion villus sampling database 1987-2000. Prenat Diagn. 2006 May;26(5):420-7.

Search NCBI Bookshelf: Chorionic Villus Sampling

Search PubMed: Search May 2006 "Chorionic Villus Sampling" 2,229 reference articles of which 261 were reviews.

Search term = Chorionic Villus Sampling

Glossary of Terms

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Where to Next?

Look at types of Abnormal Development that can occur during development.

Alternatively, look at normal development. Development Notes

Quick Links

Finally

For those wanting to see dynamic processes of development (and have a reasonably quick connection) then the Movies pages are good for watching changes occur.

Other Embryos

The study of human development has relied extensively on studying the process in other model animals. For those wanting to see the process of development in other species then the other embryos pages are a good start.

UNSW Embryology ISBN: 978 0 7334 2609 4

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