NiceProt View of SWISS-PROT: P11487

[General] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

General information about the entry
Entry name	FGF3_HUMAN
Primary accession number	P11487
Secondary accession number(s)	None
Entered in SWISS-PROT in	Release 12, October 1989
Sequence was last modified in	Release 12, October 1989
Annotations were last modified in	Release 38, July 1999
Name and orig in of the protein
Protein name	INT-2 PROTO-ONCOGENE PROTEIN [Precursor]
Synonym(s)	FIBROBLAST GROWTH FACTOR-3 FGF-3 HBGF-3
Gene name(s)	FGF3 OR INT2
From	Homo sapiens (Human)
Taxonomy	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Mammalia; Eutheria; Primates; Catarrhini; Hominidae; Homo.
References
[1] SEQUENCE FROM N.A. TISSUE=PLACENTA; MEDLINE; 89239468. [NCBI, ExPASy, Israel, Japan] Brooks S., Smith R., Casey G., Dickson C., Peters G.; "Sequence organization of the human int-2 gene and its expression in teratocarcinoma cells."; Oncogene 4:429-436(1989).
Comments
FUNCTION: COULD BE INVOLVED IN EAR DEVELOPMENT. SIMILARITY: BELONGS TO THE HEPARIN-BINDING GROWTH FACTORS FAMILY.
Copyright
This SWISS-PROT entry is copyright. It is produced through a collaboration between the Swiss Institute of Bioinformatics and the EMBL outstation - the European Bioinformatics Institute. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See http://www.isb-sib.ch/announce/ or send an email to license@isb-sib.ch).
Cross-references
EMBL X14445; CAA32615.1; -. [EMBL / GenBank / DDBJ] [CoDingSequence] PIR S04742; S04742. HSSP P09038; 2BFH. [HSSP ENTRY / SWISS-3DIMAGE / PDB] MIM 164950; -. GeneCards FGF3. PRINTS PR00262; IL1HBGF. PR00263; HBGFFGF. PROSITE PS00247; HBGF_FGF; 1. PFAM PF00167; FGF; 1. PRODOM [Domain structure / List of seq. sharing at least 1 domain] BLOCKS P11487. DOMO P11487. PROTOMAP P11487. PRESAGE P11487. SWISS-2DPAGE GET REGION ON 2D PAGE.
Keywords
Transforming protein; Oncogene; Growth factor; Mitogen; Signal; Glycoprotein.
Features
SIGNAL 1 17 POTENTIAL. CHAIN 18 239 INT-2 PROTO-ONCOGENE PROTEIN. CARBOHYD 65 65 POTENTIAL. FT table viewer
Sequence information
Length: 239 AA [This is the length of the unprocessed precursor] Molecular weight: 26886 Da [This is the Mw of the unprocessed precursor] CRC64: 8DBEF17D2B2E3C63 [This is a checksum on the sequence]
10 20 30 40 50 60 | | | | | | MGLIWLLLLS LLEPGWPAAG PGARLRRDAG GRGGVYEHLG GAPRRRKLYC ATKYHLQLHP 70 80 90 100 110 120 | | | | | | SGRVNGSLEN SAYSILEITA VEVGIVAIRG LFSGRYLAMN KRGRLYASEH YSAECEFVER 130 140 150 160 170 180 | | | | | | IHELGYNTYA SRLYRTVSST PGARRQPSAE RLWYVSVNGK GRPRRGFKTR RTQKSSLFLP 190 200 210 220 230 239 | | | | | | RVLDHRDHEM VRQLQSGLPR PPGKGVQPRR RRQKQSPDNL EPSHVQASRL GSQLEASAH P11487 in FASTA format